Metabolism of nucleic acids during regeneration of wound tissue. III. The rate of formation of DNA [0.03%]
论伤口愈合过程中核酸的代谢。第三章：论DNA形成的速率
W GUSCHLBAUER,M B WILLIAMSON
W GUSCHLBAUER
Oxidative stress reduces transintestinal transports and (Na+, K+) -ATPase activity in rat jejunum [0.03%]
氧化应激减少大鼠空肠的转运和(Na+，K+)- ATP酶活性
Maria Novella Orsenigo,Alide Faelli,Cristina Porta et al.
Maria Novella Orsenigo et al.
Because oxidative stress is a component of gastrointestinal injury, we investigated the effect of H(2)O(2) on transintestinal transport using isolated rat jejunum incubated in vitro. Millimolar concentrations of H(2)O(2) inhibited all the t...
Metabolic impact of overexpression of liver glycogen synthase with serine-to-alanine substitutions in rat primary hepatocytes [0.03%]
大鼠原代肝细胞过表达含丝氨酸到丙氨酸替换的肝脏糖原合成酶对代谢的影响
Akito Kadotani,Maho Fujimura,Takao Nakamura et al.
Akito Kadotani et al.
To investigate the effect of elevation of liver glycogen synthase (GYS2) activity on glucose and glycogen metabolism, we performed adenoviral overexpression of the mutant GYS2 with six serine-to-alanine substitutions in rat primary hepatocy...
Curcumin suppresses the transformation of an aryl hydrocarbon receptor through its phosphorylation [0.03%]
姜黄素通过磷酸化抑制芳烃受体的转化
Shin Nishiumi,Ken-Ichi Yoshida,Hitoshi Ashida
Shin Nishiumi
Halogenated and polycyclic aromatic hydrocarbons induce diverse biochemical responses through the transformation of a cytosolic aryl hydrocarbon receptor (AhR). In mouse hepatoma Hepa-1c1c7 cells, curcumin, a yellow pigment of Curcuma longa...
Dietary flavonoid apigenin is a potential inducer of intracellular oxidative stress: the role in the interruptive apoptotic signal [0.03%]
饮食类黄酮植物化学物芹菜素诱导细胞内氧化应激及其对抗凋亡信号的作用机制研究
Noriyuki Miyoshi,Kisa Naniwa,Takayo Yamada et al.
Noriyuki Miyoshi et al.
Apigenin is a representative dietary flavone (2-phenyl-4H-1-benzopyran-4-one) inhibiting cancer cell growth both in cell culture systems and in vivo. The prooxidant potential of apigenin was confirmed by the observations using flowcytometri...
Identification of calpastatin and mu-calpain and studies of their association in pulmonary smooth muscle mitochondria [0.03%]
钙调神经磷酸酶和μ-钙蛋白酶的鉴定及其在肺平滑肌线粒体中的相互作用研究
Pulak Kar,Tapati Chakraborti,Soumitra Roy et al.
Pulak Kar et al.
Using calpastatin antibody we have identified a 145 kDa major band along with two relatively minor bands at 120 kDa and 110 kDa calpastatin molecules in bovine pulmonary artery smooth muscle mitochondria. To the best of our knowledge this i...
Myeloperoxidase-catalyzed taurine chlorination: initial versus equilibrium rate [0.03%]
髓过氧化物酶催化的牛磺酸氯化：初始速率与平衡速率的区别
Daniel R Ramos,M Victoria García,Moisés Canle L et al.
Daniel R Ramos et al.
Myeloperoxidase (MPO) catalyzes the two-electron oxidation of chloride, thereby producing hypochlorous acid (HOCl). Taurine (2-aminoethane-sulfonic acid, Tau) is thought to act as a trap of HOCl forming the long-lived oxidant monochlorotaur...
Cell cycle-dependent caspase-like activity that cleaves p27(KIP1) is the beta(1) subunit of the 20S proteasome [0.03%]
周期依赖的类似半胱天冬酶活性切割p27(KIP1)是20S蛋白酶体β(1)亚单位
Winston S Tambyrajah,Lucas D Bowler,Cahora Medina-Palazon et al.
Winston S Tambyrajah et al.
We previously described a caspase-like activity, which we termed KIPase that is implicated in the turnover of the mammalian cell cycle regulator p27(KIP1). KIPase cleaves a tetra-peptide substrate, Ac-DPSD-AMC, which mimics the target site ...
Isoforms of alanine aminotransferases in human tissues and serum--differential tissue expression using novel antibodies [0.03%]
人类组织和血清中的丙氨酸氨基转移酶同工型-利用新型抗体进行差异表达分析
Per Lindblom,Ingalill Rafter,Clive Copley et al.
Per Lindblom et al.
Serum alanine aminotransferase (ALT) is used as a clinical marker of hepatotoxicity. Two forms of ALT have been identified, ALT1 and ALT2, encoded by separate genes. The cellular and tissue distribution of the different ALT proteins has not...
Houfang Wang,Yanhui Tang,Ming Lei
Houfang Wang
Here, molecular dynamics (MD) simulations are performed to study the differences of binding channel shapes of TTR with two inhibitors, flufenamic acid (FLU) and one kind of N-phenyl phenoxazine (BPD). The asymmetries of global structure inc...