Modern Nanocarriers as a Factor in Increasing the Bioavailability and Pharmacological Activity of Flavonoids [0.03%]
现代纳米载体作为提高黄酮类生物利用度和药理活性的因素
Ya F Zverev,A Ya Rykunova
Ya F Zverev
This review is devoted to modern systems of nanocarriers that ensure the targeted delivery of flavonoids to various organs and systems. Flavonoids have wide range of effects on the human body due to their antioxidant, anti-inflammatory, ant...
The Effect of Disinfectants on the SARS-CoV-2 RNA Detection in Swabs from Various Surfaces [0.03%]
消毒剂对从各种表面的拭子中检测SARS-CoV-2 RNA的影响
M S Krasnikova,E A Lazareva,S P Yatsentyuk
M S Krasnikova
The COVID-19 pandemic has spread rapidly around the world; some countries have introduced controls on imported products, including testing for viral nucleic acids. In this work, the influence of disinfectants for treating various SARS-CoV-2...
Rapid Assessment of Neutralizing Antibodies Using Influenza Viruses with a Luciferase Reporter [0.03%]
使用带有荧光素酶报告系统的流感病毒快速评估中和抗体
M V Sergeeva,A A Pulkina,E A Romanovskaya-Romanko et al.
M V Sergeeva et al.
Influenza viruses cause acute respiratory infections, especially in the autumn-winter period. They are characterized by a high mutation frequency and cause annual seasonal epidemics. The detection of antibodies that neutralize the virus is ...
Microalgae in Terms of Biomedical Technology: Probiotics, Prebiotics, and Metabiotics [0.03%]
从生物医学技术的角度看微藻：益生元，益生素和代谢物
A V Oleskin,Cao Boyang
A V Oleskin
Green, red, brown, and diatomic algae, as well as cyanobacteria, have been in the focus of attention of scientists and technologists for over 5 decades. This is due to their importance as efficient and economical producers of food additives...
R A Yunes,E U Poluektova,T V Belkina et al.
R A Yunes et al.
The global probiotics industry has been undergoing major changes in recent years. Approaches to finding and creating new probiotics, as well as a paradigm of their use in food, medicine, and pharmacology are changing. The catalyst proved to...
Synthesis of a Bioactive Composition of Chitosan-Selenium Nanoparticles [0.03%]
壳聚糖-硒纳米颗粒生物活性复合材料的合成
K V Apryatina,E I Murach,S V Amarantov et al.
K V Apryatina et al.
A biologically active composition of chitosan-selenium nanoparticles has been developed. Selenium nanoparticles are characterized by a clear bimodal size distribution: 2-3 and ~37 nm. The main active centers of complexation with nanoparticl...
Streptomyces tsukubensis VKM Aс-2618D-an Effective Producer of Tacrolimus [0.03%]
黏红抗生素丝状杆菌VKM Aс-2618D-他克莫司的有效产生菌株
V Yu Poshekhontseva,V V Fokina,S V Tarlachkov et al.
V Yu Poshekhontseva et al.
The Streptomyces sp. VKM Ac-2618D strain has been identified, and its morphological and physiological features have been studied in relation to the production of the immunosuppressant tacrolimus. The phenotypic variability of the strain was...
Loop-Mediated Isothermal Amplification as a Promising Method for Mass COVID-19 Diagnostics [0.03%]
环介导等温扩增技术有望用于大规模新冠肺炎检测
J A Makarova,K A Fomicheva,A I Osipyants et al.
J A Makarova et al.
Real-time reverse-transcription polymerase chain reaction (RT-PCR) is currently the most popular method for early COVID-19 diagnostics. However, loop-mediated isothermal amplification (LAMP) is superior to real-time RT-PCR in rapidity and s...
CRISPR Interference of Adenylate Cyclases from Mycobacterium tuberculosis [0.03%]
利用CRISPR干扰技术抑制结核分枝杆菌的腺苷酸cyclase功能
N I Nadolinskaia,M V Zamakhaev,M S Shumkov et al.
N I Nadolinskaia et al.
This work describes a modification of the pRH2521 vector of the pRH2502/pRH2521 system for CRISPR-dCas9-mediated RNA interference. The modification enabled an increase in the cloning efficiency of guide RNA spacers. The ability of the modif...
Use of Mathematical Methods for the Biosafety Assessment of Agricultural Crops [0.03%]
数学方法在农业作物生物安全评价中的应用
E V Korotkov,I V Yakovleva,A M Kamionskaya
E V Korotkov
In Russia and around the world, there are important questions regarding the potential threats to national and biological safety created by genetic technologies and the need to improve or introduce new, justified, and adequate measures for t...