Optimization of UV Spectrophotometric Techniques for Tafamidis Meglumine Detection in Pharmaceutical Formulations and Biological Samples: A Green Chemistry Perspective [0.03%]
基于绿色化学的药物制剂和生物样品中Tafamidis Meglumine检测的UV光谱法优化研究
Md Mojeeb G Khan,Shubham R Raut,Md Rageeb Md Usman et al.
Md Mojeeb G Khan et al.
Objectives: The primary objective was to develop and validate four novel UV/Visible spectrophotometric methods for the quantification of Tafamidis meglumine in bulk drug, proprietary capsules, and spiked urine samples, en...
Computational Genome Engineering Through AI-CRISPR-Precision Medicine Integration in Modern Therapeutics [0.03%]
人工智能与CRISPR结合的精准医疗在现代治疗中的应用及基因组工程计算学
Oluwaseun E Agboola,Samuel S Agboola,Othuke B Odeghe et al.
Oluwaseun E Agboola et al.
The convergence of precision medicine strategies, CRISPR gene editing technologies, and artificial intelligence (AI) is causing a revolutionary change in the pharmaceutical industry in recent times. Latest trends and future directions of th...
Development and Characterization of AXT@Metal-Organic Framework: A Biocompatible, pH-Responsive Nanocarrier for Targeted Axitinib Delivery in MCF-7 Cancer Cells [0.03%]
AXT@金属有机框架的开发与表征：一种生物相容性的pH响应载药体系在MCF-7癌细胞中的靶向阿昔替尼递送研究
Jayvadan K Patel,Ujashkumar A Shah,Pravin O Patil et al.
Jayvadan K Patel et al.
Cancer remains a major global health challenge, characterized by low survival rates and significant side effects from conventional treatments. The metal-organic frameworks (MOFs) offer distinctive features that make them highly suitable for...
Comparative Evaluation of the Anticancer Effects of Echium amoenum and Valeriana officinalis on U87-MG Glioblastoma Cells [0.03%]
毛地黄草和欧缬草对U87-MG胶质母细胞瘤细胞的抗癌效果比较评估研究
Maryam Mohseni,Reza Masoomi Jahandizi,Ehsan Zayerzadeh
Maryam Mohseni
Objectives: Glioblastoma (GBM) is one of the most aggressive and treatment-resistant types of brain cancer, and conventional therapies such as surgery, chemotherapy, and radiotherapy have limited effectiveness in controll...
A multidisciplinary intervention to improve postoperative antithrombotic therapy after urgent coronary artery bypass-grafts [0.03%]
提高冠状动脉旁路移植术后的术后抗血栓治疗的多学科干预措施
Alma Feka,Mario Verdugo-Marchese,Sarah Hugelshofer et al.
Alma Feka et al.
Objectives: The objective of this study was to assess whether implementing a protocol could improve adherence to European guidelines on postoperative antithrombotic therapy prescription in patients undergoing coronary art...
From inhibition to degradation: cutting-edge technology in COVID-19 drug discovery [0.03%]
从抑制到降解：COVID-19药物发现的前沿技术
Emmanuel Adediran,Martin Ikhoyameh,Ololade S Gbadebo
Emmanuel Adediran
Proteolysis Targeting Chimera (PROTAC) molecules are hetero-bifunctional chemical entities with three different units which include a ligand that binds to a protein of interest; a second ligand that binds to the E3 ubiquitin Ligase; and a l...
Crystal structure, spectral characterization, photophysical properties, Hirshfeld surface analysis, and antimicrobial activity of homopiperazinium dichromate(VI) [0.03%]
同piperazinium二铬酸盐(VI)的晶体结构、光谱特征、光物理性质、Hirshfeld表面分析及抗菌活性
Utkirjon Holikulov,Sonia Trabelsi,Houda Marouani et al.
Utkirjon Holikulov et al.
This work presents a comprehensive study of the crystal structure, spectral properties (IR and UV-Vis), thermal behavior, and antimicrobial activity of homopiperazinium dichromate (C5H14N2)Cr2O7(VI). X-ray diffraction reveals that the compo...
"Synthesizing Safety Data on Novel Intravaginal Formulations: A Comprehensive Scoping Review of In vivo and In vitro Research" [0.03%]
“新型阴道制剂安全数据的综合分析：体内和体外研究的全面综述性回顾”
T P Athul,Anjani Seth,Vanshika Sharma et al.
T P Athul et al.
Background and objectives: Intravaginal drug delivery systems are gaining attention for their potential to treat local and systemic gynaecological conditions, offering advantages such as bypassing hepatic first-pass metab...
Laggera pterodonta: Traditional uses, phytochemistry and biological activities [0.03%]
拉格拉草的傳統用途、植物化學和生物活性
Pham Van Huyen,Nguyen Thi Thu Hien,Tran Thi Ngoc Hanh et al.
Pham Van Huyen et al.
Laggera pterodonta is a promising medicinal plant with multiple therapeutic applications, supporting its traditional use and potential for modern drug development. With its diverse bioactive constituents such as flavonoids, terpenoids, phen...
[Impact of Therapeutic Education on Knowledge, Adherence, Asthma Control, and Respiratory Function in Asthmatic Patients: A 6-Month Follow-Up] [0.03%]
基于哮喘教育对哮喘患者临床结局影响的病例对照研究-followup 6个月
Faiza Sebhi,Adjou Lydia,Rania Bazia et al.
Faiza Sebhi et al.
Introduction: Therapeutic patient education (TPE) is a key component in the management of asthma. This study aims to assess the impact of TPE on disease control, treatment adherence, lung function, and the frequency of ho...