Potential Role of SESN3 in Linking Heart Failure with Preserved Ejection Fraction and Chronic Obstructive Pulmonary Disease via Autophagy Dysregulation [0.03%]
SESN3在心力衰竭伴射血分数保留与慢性阻塞性肺病相关性中的自噬调节作用及其潜在机制
Rongxin Zhu,Binhua Yuan,Yunlin Li et al.
Rongxin Zhu et al.
These results provide novel insights into the potential multi-organ involvement in HFpEF and support the role of SESN3 as a shared molecular target in both cardiac and pulmonary pathologies.
Potential Probiotic Lacticaseibacillus rhamnosus NKU FL1-11 Prevents Aging-Related Oxidative Stress and Inflammation via mTOR and FoxO Signaling Pathways in Zebrafish [0.03%]
植物乳杆菌NKU FL1-11通过雷帕霉素复合体1和叉头盒转录因子O途径预防衰老相关氧化应激和炎症反应
Dan Li,Xiang Gao,Weiye Liu et al.
Dan Li et al.
Aging, a complex physiological process characterized by multi-organ involvement and closely associated with oxidative stress and chronic inflammation, has prompted growing scientific interest in natural antioxidant probiotics due to their dual health-promoting properties and anti-oxidative capabilities
Allogeneic CD19-targeted CAR-T therapy in refractory systemic lupus erythematosus achieved durable remission [0.03%]
同种异体CD19靶向CAR-T治疗难治性系统性红斑狼疮获得持续缓解
Dandan Wang,Xiaobing Wang,Binghe Tan et al.
Dandan Wang et al.
Methods: In this study, 3 patients with refractory and severe SLE with multi-organ involvement were enrolled. Genetically engineered healthy-donor-derived, CD19-targeting CAR-T cells were infused intravenously at a dose of 1 million cells per kilogram of body weight.
Vitamin D Imbalance and Hydro-Electrolyte Disturbances in Hospitalized Children: A Comparation Between Post-COVID-19 Status and SARS-CoV-2/EBV Coinfection [0.03%]
住院儿童维生素D失衡与水电解质紊乱：新冠病毒感染后状态与EBV合并感染的比较研究
Carmen Loredana Petrea Cliveți,Diana-Andreea Ciortea,Gabriela Gurău et al.
Carmen Loredana Petrea Cliveți et al.
Background/Objectives: SARS-CoV-2 infection has the potential to cause multi-organ involvement and, when associated with Epstein-Barr virus (EBV) coinfection, may worsen the course of disease in pediatric patients by influencing the immune response.
Deepening Understanding of the Clinical Features and Diagnostic Approaches to Anti-Interferon-Gamma Autoantibody Associated Adult-Onset Immunodeficiency in the Last 20 Years: A Case Report and Literature Review [0.03%]
既往二十年干扰素γ自身抗体相关成人发病原发性免疫缺陷临床特征及诊断进展——一例报告与文献复习
Liyan Zhao,Jindi Ma,Ying Sun et al.
Liyan Zhao et al.
The clinical manifestations are diverse and non-specific for the disease often presenting with multi-organ involvement and multiple infections.
IgA nephropathy, non-cirrhotic portal fibrosis, and POEMS syndrome: A rare combination in the long-term follow-up of Sjögren's syndrome [0.03%]
干燥综合征长期随访中出现一种罕见的并发症组合：IgA肾病、非肝硬化门脉纤维化和POEMS综合征
Xiuhong Wang,Lina Zhang,Tong Zhang et al.
Xiuhong Wang et al.
Valuable pathological information of multi-organ involvement as well as detailed clinical course were presented to facilitate further understanding of this rare entity.
Pediatric Autoimmune Pancreatitis: Clinical Findings and Outcomes in Sweden [0.03%]
瑞典儿童自身免疫性胰腺炎的临床特征和结局
Miroslav Vujasinovic,Fredrik Lindgren,Nikolaos Kartalis et al.
Miroslav Vujasinovic et al.
Conclusions: Pediatric AIP is a rare condition often associated with multi-organ involvement particularly IBD. Most patients respond well to glucocorticoid treatment and achieve remission.
Anouk Morier-Genoud,Laurent Christin
Anouk Morier-Genoud
With multi-organ involvement due to septic emboli, the evolution is quickly severe and patient dies during hospital stay.
Orbital and ocular adnexal histiocytic tumors; a multidisciplinary literature review [0.03%]
orbital和眼附属器组织细胞肿瘤；多学科文献综述
Seyed Mohammad Malakooti Shijani,Mohsen Bahmani Kashkouli,Mercia J Bezerra Gondim et al.
Seyed Mohammad Malakooti Shijani et al.
Systemic chemotherapy is the primary treatment for EDC, RDD, and HS and the treatment of choice for the patients with multifocal or multi-organ involvement as well as recurrent or refractory lesions, regardless of the type of histiocytic tumor.
Multi-organ Involvement in Catastrophic Antiphospholipid Syndrome: A Challenging Case with a Fatal Outcome [0.03%]
重症抗磷脂综合征多器官受累的一例致命病例挑战
Selma Özlem Çelikdelen,Reyhan Bilici
Selma Özlem Çelikdelen
Catastrophic antiphospholipid syndrome (CAPS) is a rare, life-threatening variant of antiphospholipid syndrome (APS) characterized by extensive thrombosis, multi-organ involvement, and high mortality. Despite advances in the understanding a...
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