Cord blood proteomics identifies biomarkers of early-onset neonatal sepsis [0.03%]
基于脐带血的蛋白质组学鉴定出早期新生儿败血症生物标志物
Leena B Mithal,Mark E Becker,Ted Ling-Hu et al.
Leena B Mithal et al.
Conclusion: These results suggest that cord blood biomarker screening may be useful for early stratification of EOS risk among neonates, improving targeted, evidence-based use of antibiotics early in life.
Targeting early diagnosis and treatment of pancreatic cancer among the diabetic population: a comprehensive review of biomarker screening strategies [0.03%]
针对糖尿病人群胰腺癌的早期诊断和治疗：生物标志物筛查策略的全面回顾
Jie Yang,Chengming Wen,Hongkai Guo et al.
Jie Yang et al.
We further evaluate current biomarker screening approaches for PDAC within diabetic subpopulations, assess the effectiveness of screening programs among high-risk groups, and propose practical strategies for the early identification and monitoring of PDAC....Early detection in diabetic individuals through targeted biomarker screening followed by timely therapeutic intervention may significantly reduce mortality, improve survival rates, and extend patient longevity.
Comprehensive and high-coverage glycerophospholipidomic analysis based on iterative quadrupole time-of-flight mass spectrometry and its application in cerebral ischemia-reperfusion injury [0.03%]
基于四极杆飞行时间质谱迭代分析的全面高覆盖磷脂组学研究及其在脑缺血再灌注损伤中的应用
Biqiong Qu,Menghan Feng,Lirong Liu et al.
Biqiong Qu et al.
Overall, this iterative MS/MS approach extensively expanded the coverage of low-abundance components, and has been proven to be an effective approach in biomarker screening of cerebral ischemia-reperfusion injury.
Optimized efficient screening for Duchenne muscular dystrophy carriers using proto-oncogene tyrosine-protein kinase receptor Ret [0.03%]
优化的RET基因筛选方法在抗凝血状态下的杜氏肌营养不良症携带者筛查中的应用研究
Dongyang Hong,Zhilei Zhang,Yun Sun et al.
Dongyang Hong et al.
The CK-MM/RET ratio was calculated, and a receiver operating characteristic curve analysis evaluated biomarker screening efficiency.
Dual Cas12a and multiplex crRNA CRISPR strategy ultrasensitive detection novel circRNA biomarker for the diagnosis of ovarian cancer [0.03%]
双重Cas12a和多重crRNA的CRISPR策略超灵敏检测新型环状RNA生物标志物以诊断卵巢癌
Lingxi Tian,Yan Gao,Lihan Zi et al.
Lingxi Tian et al.
Conclusions: The DCMC-CRISPR platform offers a promising solution for circRNA biomarker screening and circRNA diagnostic.
A deep learning framework for enhanced mass spectrometry data analysis and biomarker screening [0.03%]
一种用于增强质谱数据评估和生物标志物筛查的深度学习框架
Shuyu Zhang,Zhiyu Li,Weili Peng et al.
Shuyu Zhang et al.
Mass spectrometry (MS) serves as a powerful analytical technique in metabolomics. Traditional MS analysis workflows are heavily reliant on operator experience and are prone to be influenced by complex, high-dimensional MS data. This study i...
DNA methylation detection is a significant biomarker for screening endometrial cancer in premenopausal women with abnormal uterine bleeding [0.03%]
DNA甲基化检测可作为绝经前异常子宫出血女性子宫内膜癌筛查的重要生物标志物
Xingping Zhao,Yanfei Yang,Yinqin Fu et al.
Xingping Zhao et al.
Objective: The aim of our study was to explore the value of DNA (CDO1m/CELF4m) methylation detection in exfoliated cervical cells collected for screening endometrial cancer in premenopausal women with abnormal uterine ble...
Bacterial diversity and biomarkers screening of station and carriage surface in Shanghai metro system, China [0.03%]
中国上海地铁站和车厢表面细菌多样性和生物标志物筛查
Lijun Zhang,Xiaojing Li,Lisha Shi et al.
Lijun Zhang et al.
This work serves as a reference for understanding the composition and dynamics of bacterial communities and for biomarker screening in subways, a crucial public space in our increasingly urbanized and interconnected world.
Causal Analysis Between Gut Microbes, Aging Indicator, and Age-Related Disease, Involving the Discovery and Validation of Biomarkers [0.03%]
关于肠道微生物、衰老标志物和与年龄相关疾病之间因果分析的研究，包括生物标志物的发现和验证
Chunrong Lu,Xiaojun Wang,Xiaochun Chen et al.
Chunrong Lu et al.
The influence of gut microbes on aging has been reported in several studies, but the mediating pathways of gut microbiota, whether there is a causal relationship between the two, and biomarker screening and validation have not been fully discussed.
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