Adriana E Cisneros,Ana Alarcia,Juan José Llorens-Gámez et al. Adriana E Cisneros et al.

Our results reveal that syn-tasiRNA precursors can be significantly shortened without compromising silencing efficacy, and that syn-tasiR-VIGS represents a versatile, scalable, and nontransgenic platform for precision RNA interference and antiviral vaccination in plants.

Shiva Hemmati,Haniyeh Rasekhi Kazerooni Shiva Hemmati

While antibiofilm and wound-healing peptides were detected in Synanceia verrucosa, APC epitopes as universal adjuvants for antiviral vaccination were in Pterois volitans and Conus monile.

Laura Marongiu,Mihai Valache,Fabio A Facchini et al. Laura Marongiu et al.

Here we illustrate these various aspects of the antiviral functions of DCs and also provide a brief overview of novel antiviral vaccination strategies based on DCs targeting.

Saborni Chattopadhyay,Che-Ming Jack Hu Saborni Chattopadhyay

While many STING-activating nanoparticles are developed to enhance anticancer immunotherapy, their adoption as vaccine adjuvant has vastly propelled antiviral vaccination efforts against challenging public health threats, including HIV, influenza and coronaviruses.

January Weiner,David J M Lewis,Jeroen Maertzdorf et al. January Weiner et al.

Six antiviral vaccination strategies were evaluated to generate training data-sets of pre-/post-vaccination vital signs, blood changes and whole-blood gene transcripts, and to identify putative biomarkers of early inflammation/reactogenicity that could guide the design of subsequent focused confirmatory

Emilie Bernichon,Sophie Espenel,Benoite Méry et al. Emilie Bernichon et al.

Preventive antiviral vaccination has become a real public health issue and aims to effectively reduce the prevalence of cervical, anal and oropharynx cancer, HPV-associated. However, vaccination against HPV still lags behind.

Susana Magadan,Luc Jouneau,Maximilian Puelma Touzel et al. Susana Magadan et al.

Vaccination induces "public" antibody clonotypes common to all individuals of a species, that may mediate universal protection against pathogens. Only few studies tried to trace back the origin of these public B-cell clones. Here we used Il...

Saswati S Lenka,Mahismita Paichha,Madhubanti Basu et al. Saswati S Lenka et al.

The high-mobility group box 1 (HMGB1) protein is a highly conserved nonhistone chromosomal protein ubiquitously present in almost all cell types. In the nucleus, it facilitates DNA repair and replication, V(D)J recombination, stabilization ...

Alan M Watson,L K Metthew Lam,William B Klimstra et al. Alan M Watson et al.

A gold standard of antiviral vaccination has been the safe and effective live-attenuated 17D-based yellow fever virus (YFV) vaccines. Among more than 500 million vaccinees, only a handful of cases have been reported in which vaccinees developed a virulent wild type YFV infection.

Katharina Hochheiser,Marika Klein,Catherine Gottschalk et al. Katharina Hochheiser et al.

Protective immunity against intracellular pathogens involves the induction of robust CTL responses. Vaccination with protein Ags establishes such responses only when combined with immune-stimulatory adjuvants. In this study, we compared dif...