The human gut microbiome and its metabolic pathway dynamics before and during HIV antiretroviral therapy [0.03%]
人类肠道微生物组及其在开始接受抗逆转录病毒治疗前后代谢途径的动态变化
Oumar Dolo,Fousseini Coulibaly,Anou M Somboro et al.
Oumar Dolo et al.
This study aims to describe and compare intestinal microbial compositions and derived metabolic pathways in people living with HIV (PL-HIV) from prior to antiretroviral therapy (ART) to 6 and 12 months after ART initiation, compared to HIV-negative individuals....This provides additional insights into the relationship between antiretroviral therapy and the microbiome, potentially leading to new prevention and treatment strategies such as probiotic/prebiotic or microbiota transplants.
Comparison of Efavirenz and Dolutegravir on Gut Microbiome and Gut Barrier Functions [0.03%]
依非韦伦与多替拉韦对肠道微生物组和肠屏障功能比较研究
Yong-Xiang Huang,Qin Tang,Shi-Hua Fu et al.
Yong-Xiang Huang et al.
Dolutegravir (DTG) is increasingly replacing efavirenz (EFV) as the recommended first-line antiretroviral therapy (cART) component due to its superior tolerance.
The Effectiveness of Antiretroviral Therapy in Mitigating New HIV Infections in Southwest China: An Ecological Study [0.03%]
抗逆转录病毒治疗在中国西南地区减少新发艾滋病毒感染的有效性：生态学研究
Xiwei Sun,Hang Chen,Shu Liang et al.
Xiwei Sun et al.
Background: Antiretroviral therapy (ART) has been shown to reduce the number of local HIV (Human Immunodeficiency Virus) reported cases; however, there is insufficient research on the relationship between new HIV infectio...
Long-term protection from TB preventive treatment among people with HIV in a high-burden tuberculosis setting: an observational cohort study from India [0.03%]
在印度高负担结核病环境中进行的一项观察性队列研究：HIV感染者长期接受结核预防治疗的效果
Reshu Agarwal,Melissa Nyendak,Nalini Chava et al.
Reshu Agarwal et al.
There is limited evidence on its long-term protective effect among people living with HIV (PLWH) receiving antiretroviral therapy (ART) in high-burden programmatic settings.
Clinical Evaluation of Drug-Drug Interactions Between Bictegravir and Strong Inhibitors/Inducers of the CYP3A4, UGT1A1, or P-gp Pathways [0.03%]
贝卡特格韦与强CYP3A4、UGT1A1或P-糖蛋白抑制剂和诱导剂药物间相互作用的临床评价
Priyanka Arora,Hui Liu,John Ling et al.
Priyanka Arora et al.
In addition to antiretroviral therapy (ART), people with HIV often take medications to treat comorbidities. It is therefore important to assess these medications for potential drug-drug interactions, which may affect the safety and efficacy of ART.
Health-Related Quality of Life Among People Living with HIV in Vietnam, a Three-Year Longitudinal Analysis [0.03%]
越南艾滋病患者健康相关生活质量的纵向分析（2015—2017年）
Hao T Duong,Cuong D Do,Donn J Colby et al.
Hao T Duong et al.
This study examined changes in health-related quality of life (HRQOL) among people living with HIV in Vietnam over three years following antiretroviral therapy (ART) initiation. We analyzed data from a randomized trial of 639 ART-naïve patients in which HRQOL was measured using the SF-8 instrument.
Tushar Sharma,Bhavina Sharma,Rahul Chaudhary et al.
Tushar Sharma et al.
However, the type of cardiac conditions seen in this population has changed substantially since the introduction of antiretroviral therapy (ART). Coronary artery disease (CAD) has emerged as a leading cause of morbidity and mortality in HIV positive individuals.
Characterizing the HIV care continuum among children and adolescents with HIV in eastern and southern Africa in the era of "Universal Test and Treat": A systematic review and meta-analysis [0.03%]
“检测和治疗”时代东非和南部非洲儿童及青少年HIV护理连续性现状系统评价和meta分析
Nel Jason L Haw,Marcela Banegas,Sita Lujintanon et al.
Nel Jason L Haw et al.
Introduction: The "Universal Test and Treat" (UTT) era for antiretroviral therapy (ART) increased HIV service delivery to children and adolescents aged 0-19 with HIV. The goal is to reach ≥95% of people with HIV diagnosed, receiving ART and virally suppressed.
Rita Casetti,Fabiola Ciccosanti,Harpreet Kaur Lamsira et al.
Rita Casetti et al.
Results: In this study, we investigated the relationship between serum vitamin D₃ levels and the expression of autophagy markers in peripheral blood mononuclear cells from different categories of PWH: PWH under antiretroviral therapy (ART) with either normal vitamin D₃ levels or hypovitaminosis
Humoral and cellular immune responses in people living with HIV following successive COVID-19 vaccine booster doses [0.03%]
HIV感染者接种新冠疫苗加强针后的体液免疫和细胞免疫反应
José L Casado,Pilar Vizcarra,Adrián Martín-Hondarza et al.
José L Casado et al.
Methods: A prospective study followed 151 PLWH on suppressive antiretroviral therapy who completed initial COVID-19 vaccination and received two additional vaccine doses.
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