[Tripeptide polymer-based cell-imprinted hydrogels for high-efficiency circulating tumor cell capture] [0.03%]
[基于三肽聚合物的细胞印迹水凝胶高效捕获循环肿瘤细胞]
Wenjing Sun,Zhiyuan Zhang,Xinmiao Zhao et al.
Wenjing Sun et al.
The hydrogel demonstrates high selectivity， stability， and biocompatibility， offering a promising tool for clinical applications in liquid biopsy and early cancer detection.
CRISPR/Cas13a-induced self-priming cyclic amplification enables liquid biopsy of exosomal circular RNA in non-small cell lung cancer [0.03%]
基于CRISPR / Cas13a的自我引物循环放大技术在非小细胞肺癌患者外泌体环状RNA检测中的应用研究
Xiaodan Zhu,Guomin Gu,Yanli Shen et al.
Xiaodan Zhu et al.
The precise and reliable identification of circular RNA (circRNA) is essential for both biological studies and clinical diagnostics of non-small cell lung cancer (NSCLC), especially the exosomal circRNA. In this study, we utilize a CRISPR/C...
Explainable Artificial Intelligence-Driven Salivary Exosome Spectroscopic Profiling for Clinical Diagnosis and Metastasis Detection of Oral Cancer [0.03%]
基于人工智能的唾液外泌体光谱分析技术在口腔癌临床诊断及转移检测中的应用研究
Wenqian Tian,Yangcenzi Xie,Hua Su et al.
Wenqian Tian et al.
Exosome-based liquid biopsy represents a promising minimally invasive approach to cancer detection.
Liquid biopsy of plasma and urinary CfDNA differentiates glioma recurrence from radiation brain necrosis in preclinical models [0.03%]
基于液体活检的血浆和尿液中的CfDNA可区分胶质瘤模型中复发与放射性脑坏死
Junlong Sun,Chunjing Jin,Yinan Chen et al.
Junlong Sun et al.
Tissue-Specific Extracellular Vesicles Enriched From Circulation: Exploring the Liquid Biopsy Perspective [0.03%]
组织特异性外泌体富集液检测：探索液体活检的新视角
Biancamaria Pierri,Erez Eitan,Kenneth W Witwer et al.
Biancamaria Pierri et al.
Another obstacle for translating EVs into liquid biopsy applications is the wide variety of separation and characterization methods, many of which lack standardization and reproducibility....Together, these approaches will help to establish EV liquid biopsy applications as a keystone of translational medicine.
Advancements in Liquid Biopsy Technologies for Non-Invasive Detection of Placental Dysfunction and Perinatal Complications: Focus on cfDNA, cfRNA, and Extracellular Vesicles [0.03%]
非侵入性检测胎盘功能障碍和围产期并发症的液体活检技术进展：cfDNA、cfRNA 和细胞外囊泡为重点
Mishu Mangla,Seetu Palo,Naina Kumar
Mishu Mangla
The advent of liquid biopsy technologies has revolutionized the non-invasive monitoring of various medical conditions, including complications during pregnancy....This review discusses the advancements in liquid biopsy technologies, with a focus on their potential for early detection, monitoring, and understanding of placental dysfunction and perinatal complications.
Timbadiya Vijaykumar Mansukhbhai,Madhvika Patidar,Manjiri Chakor et al.
Timbadiya Vijaykumar Mansukhbhai et al.
Liquid biopsy is a minimally invasive method with strong potential for detecting and monitoring oral cancers. By analyzing ctDNA, CTCs, exosomes and other tumor-derived biomarkers, it enables early detection, prognosis and treatment monitor...
Cell-free DNA epigenomic profiling enables noninvasive detection and monitoring of translocation renal cell carcinoma [0.03%]
无细胞DNA表观基因组谱分析可实现转位性肾细胞癌的非侵入式检测和监测
Simon Garinet,Karl Semaan,Jiao Li et al.
Simon Garinet et al.
Conventional liquid biopsy assays that detect tumor DNA via somatic mutations or copy number alterations are unsuitable for tRCC since it often lacks recurrent genetic alterations and because fusion breakpoints are highly variable between patients.
Next-generation liquid biopsies: detecting circulating epigenetic changes to identify translocation renal cell carcinoma [0.03%]
下一代液体活检：通过检测循环表观遗传变化来识别染色体易位肾细胞癌
Katsuhiro Ito,David A Braun
Katsuhiro Ito
In this issue of the JCI, Garinet et al. reported on an epigenomic liquid biopsy approach that identified a TFE3 fusion-associated chromatin signature specific to tRCC....Epigenomic liquid biopsy is a promising framework to improve diagnostic accuracy and guide personalized management for tRCC.
PD-L1 status on circulating tumor cells: a promising predictor in advanced lung cancer with PD-1/PD-L1 immunotherapies [0.03%]
循环肿瘤细胞的PD-L1状态：在晚期肺癌中使用PD-1 / PD-L1免疫疗法的一项有希望的预测指标
Xiaoying Wei,Lin Chen,Zhonglin Yang et al.
Xiaoying Wei et al.
We explored a non-invasive alternative by assessing PD-L1 expression on circulating tumor cells (CTC PD-L1) via liquid biopsy to predict immunotherapy outcomes.
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