Bile cell-free DNA shows benefit as a potential sample for somatic mutation detection of resectable cholangiocarcinoma [0.03%]
胆汁无细胞DNA作为可切除肝内胆管癌体克突变检测样本的潜在价值
Songyao Liu,Xiaowu Ma,Hongkai Zhuang et al.
Songyao Liu et al.
This study aims to compare bile and plasma as sources for liquid biopsy in CCA genomic profiling, focusing on analytical accuracy and biomolecular stability.
Exosomes and NcRNAs in tumor: a comprehensive review and multi-perspective study [0.03%]
外泌体和非编码RNA在肿瘤中的研究综述及多角度探索
Xiaoman Zhang,Dequan Liu,Xiaochen Qi et al.
Xiaoman Zhang et al.
In addition, exosomes show great potential in liquid biopsy and targeted drug delivery, providing new biomarkers and strategies for cancer diagnosis and treatment.
Molecular intelligence and immune reconnaissance in thyroid cancer: a new paradigm for diagnosis, risk stratification, and therapeutic precision [0.03%]
分子智能和免疫侦察在甲状腺癌中的应用：诊断、风险分层和治疗精准化的新范式
Marcio J Concepción-Zavaleta,Jenyfer M Fuentes-Mendoza,Alfredo Cruz-Quintá et al.
Marcio J Concepción-Zavaleta et al.
Near-term priorities include standardizing multi-omic pipelines, validating AI across diverse populations, and expanding access to testing, while emerging tools such as liquid biopsy and patient-derived organoids are poised to enable adaptive, patient-specific management.
Selpercatinib for RET-positive advanced pancreatic cancer detected by liquid biopsy: a case-based insight [0.03%]
塞普替尼治疗液态活检发现的RET阳性晚期胰腺癌的一例报告
Tarek Assi,Tania Moussa,Cendrella Bou-Orm et al.
Tarek Assi et al.
A RET fusion (TPR - RET) was identified via liquid biopsy and confirmed on tissue biopsy. Treatment with the selective RET inhibitor selpercatinib led to rapid symptom improvement, normalization of tumor markers, and significant tumor regression.
Plasma Proteome-Driven Liquid Biopsy for Individualized Monitoring and Risk Stratification of Immune-Related Adverse Events in Checkpoint Immunotherapy [0.03%]
基于血浆蛋白质组的液体活检在检查点免疫治疗中进行个体化监测和预测免疫相关不良事件风险的应用研究
Dongxue Yan,Jingjing Xu,Dawei Wang et al.
Dongxue Yan et al.
Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy, however, their use is limited by heterogeneous and unpredictable immune-related adverse events (irAEs), which can progress to life-threatening conditions requiring inte...
Cross-modality fusion of hematology-based digital and molecular biomarkers for intelligent epidemiological screening and surveillance of hepatocellular carcinoma [0.03%]
基于血液学的数字和分子生物标志物跨模式融合用于智能肝细胞癌流行病学筛查和监测
Ningtao Cheng,Yi Tao,Junhan Yang et al.
Ningtao Cheng et al.
This study demonstrates a way to deriving actionable reference for liquid biopsy with the potential to advance early cancer detection.
Identification of diagnostic and prognostic phospholipid biomarkers in idiopathic pulmonary fibrosis via machine learning and in vivo validation [0.03%]
基于机器学习和体内验证的特发性肺纤维化诊断及预后磷脂标志物鉴定
Liqing Yang,Lian Liu,Yi Liao et al.
Liqing Yang et al.
Conclusion: This research successfully identified potential biomarkers for IPF and developed a prognostic model based on liquid biopsy and a diagnostic model based on lung tissue.
Targeting the LINC01272-FUS signal axis inhibits the migration and invasion of testicular germ cell tumors [0.03%]
靶向LINC01272-FUS信号轴可抑制睾丸生殖细胞肿瘤的转移和侵袭
Xueheng Zhao,Jian Cao,Lei Xue et al.
Xueheng Zhao et al.
Conclusion: We identified the LINC01272-FUS axis as a critical regulatory pathway in TGCTs progression, providing mechanistic insights for developing liquid biopsy biomarkers and RNA-targeted therapies.
Identifying actionable genetic mutations and microsatellite instability in liquid biopsy of colorectal cancer [0.03%]
结直肠癌液体活检中识别可操作遗传突变和微卫星不稳定状态
Neemat M Kassem,Mohamed G Seadawy,Maha Gaafar et al.
Neemat M Kassem et al.
Introduction: Colorectal cancer (CRC) is a molecularly diverse disorder arising from gradual accumulation of genetic and epigenetic changes giving interest in characterization of genetic alterations and microsatellite ins...
Making liquid-biopsy predictions usable in SCLC-calibration, transfer, and action-linked thresholds [0.03%]
使液体活检预测结果适用于小细胞肺癌 Calibration、Transfer和Action Linked阈值的作用
Francesco De Rango,Emmanuel Pio Pastore
Francesco De Rango
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