Liquid biopsy technologies offer new insights and approaches for canine cancer detection and management [0.03%]
John Robertson,Amr Sayed Issa,Nikolas Dervisis et al.
John Robertson et al.
Liquid biopsy (LBx) is the analysis of fluids such as blood, urine, saliva, or secretions to detect cancer biomarkers and circulating tumor cells. It is becoming a common investigational tool in human oncology, but less so in veterinary med...
Exosomal miR-27a-5p Helps Differentiate Parathyroid Carcinoma From Adenoma and Inhibits Apoptosis in Parathyroid Carcinoma Cells [0.03%]
Jiacheng Wang,Yuting Wang,Qian Wang et al.
Jiacheng Wang et al.
Conclusions: The exosomal miR-27a-5p assay is a noninvasive liquid biopsy method that provides an important reference for the timely and accurate identification and treatment of PC.
Bile-Derived Exosomal miR-196a/-196b as Diagnostic Biomarkers Associated With Tumor Progression in Biliary Tract Cancer [0.03%]
胆汁来源的外泌体miR-196a/-196b作为胆道癌诊断及肿瘤进展相关的生物标志物
Naotaka Kugiyama,Katsuya Nagaoka,Takehisa Watanabe et al.
Naotaka Kugiyama et al.
Bile-based liquid biopsy presents a promising approach for identifying novel biomarkers for biliary tract cancer (BTC) given its proximity to tumor sites. The aim of this study was to identify bile-derived exosomal microRNAs (miRNAs) with diagnostic potential for BTC.
Multiomic characterization of malignant pulmonary nodules and development of a methylation-based diagnostic Model [0.03%]
恶性肺结节的多组学特征分析及甲基化诊断模型的建立
Wei Zhou,Tongji Xie,Qingjun Wu et al.
Wei Zhou et al.
Our findings provide a robust theoretical foundation and a high-performance liquid biopsy tool for the precise, noninvasive diagnosis of pulmonary nodules.
Exosomes liquid biopsy in Lymphoma precision medicine: applications and challenges [0.03%]
外泌体液体活检在淋巴瘤精准医疗中的应用和挑战
Junxi Liu,Yu Peng,Yakun Zhang et al.
Junxi Liu et al.
With further research, exosome-based liquid biopsy has the potential to enhance patients' quality of life....This review summarizes the application of exosome-based liquid biopsy in lymphoma and its underlying mechanisms within the TME, emphasizing the promising opportunities this technique presents for medical research.
Screening and identification of biomarkers in tumor-educated platelets for non-small cell lung cancer [0.03%]
肿瘤衍生血小板中非小细胞肺癌生物标志物的筛选与鉴定
Zhen Xu,Wenxin Li,Yueneng Yu et al.
Zhen Xu et al.
Background: Platelets, a crucial source of liquid biopsy samples, play a significant role in the progression of various malignancies, including non-small cell lung cancer (NSCLC). However, specific biomarkers for early-stage NSCLC have not yet been identified.
Liquid Biopsy Biomarkers as Predictors of TNBC Recurrence: A Systematic Review [0.03%]
循环生物标志物在三阴性乳腺癌复发预测中的作用：系统综述
Nur Rahadiani,Dyah Laksmi Dewi,Mohammad Ghozali
Nur Rahadiani
Methods: A systematic review on liquid biopsy in TNBC was conducted and analyzed using PRISMA guidelines and later assessed via the EPHPP tool.
Target-triggered assembly of engineered bacteria enables dual-mode detection of microRNA [0.03%]
工程细菌的目标触发组装实现microRNA的双模式检测
Xuemei Wang,Ye Li,Heng Zhou et al.
Xuemei Wang et al.
This work demonstrates that interfacial engineering transforms engineered bacteria into multifunctional living sensing units and provides a practical strategy for developing reliable biosensing systems for liquid biopsy applications.
Evaluating the investigational drug landscape for ESR1-mutated, estrogen receptor positive, HER2 negative metastatic breast cancer [0.03%]
评估ESR1突变型、雌激素受体阳性、HER2阴性转移性乳腺癌的在研药物格局
Marie Kroemer,Morgane Lopez,Laura Mansi et al.
Marie Kroemer et al.
Expert opinion: Routine assessment of ESR1 mutations using liquid biopsy should be integrated into clinical practice to enable dynamic, molecularly guided treatment optimization.
Molecular Encoding during Amplification Enables Multiplex Nanopore Profiling of Small Noncoding RNAs [0.03%]
扩增过程中分子编码使小非编码RNA的多重纳米孔谱分析成为可能
Mengyu Liu,Haotian Zhang,Sha Guo et al.
Mengyu Liu et al.
This amplification-encoded nanopore strategy provides a scalable framework for multiplex single-molecule analysis of diverse sncRNAs and highlights its potential for liquid biopsy applications.
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