Single tube cell-free transcription and autocatalytic signal amplification based fluorescent biosensor for microRNA detection [0.03%]
Qian Xie,Ming Chen,Zhenyu Lin
Qian Xie
This work presents a rapid, sensitive, and easy-to-use strategy for miRNA quantification, offering a robust tool for point-of-care testing and liquid biopsy applications.
Exosomes in diabetic kidney disease: pathogenesis, biomarker discovery, and emerging therapeutics-a comprehensive systematic review [0.03%]
Lin Ding,Zuolin Li,Yan Xia et al.
Lin Ding et al.
Accumulating evidence has revealed dynamic alterations in the quantity and composition of urinary exosomes under diabetic conditions, implicating these vesicles in the multifactorial pathogenesis of DKD and highlighting their promise as liquid biopsy biomarkers for DKD.
Julian Wolf
Julian Wolf
A selective enrichment and specific probe terminal mediated strategy for highly sensitive detection of microRNAs [0.03%]
Zecheng Zhong,Weida Huang,Jinhua Ren et al.
Zecheng Zhong et al.
MicroRNAs are promising liquid biopsy biomarkers, but their clinical translation is hindered by detection challenges, including low abundance, high sequence similarity, and background interference.
Lotta Eriksson,Eszter Lakatos
Lotta Eriksson
To address this challenge, we developed BayesCNA, a method designed to improve signal extraction from low-pass liquid biopsy sequencing data, by utilizing a Bayesian changepoint detection algorithm.
Active nanorobotic systems for blood-based detection of cancer biomarkers: from passive nanosensors to dynamic liquid biopsy platforms [0.03%]
Subham Preetam,Pratyasa Rath,Chellasamy Panneerselvam et al.
Subham Preetam et al.
Circulating-tumour DNA (ctDNA) in NSCLC: mechanisms, evidence and the future of MRD detection [0.03%]
Beatriz Jimenez-Munarriz,Berenice Urtecho,Mary R Rabey et al.
Beatriz Jimenez-Munarriz et al.
This review highlights the growing role of liquid biopsy as a predictive and prognostic tool in non-small cell lung cancer management.
Tumor-informed liquid biopsy detection of structural variants in high grade serous ovarian cancer [0.03%]
Jian Li,Shiro Takamatsu,Allison L Brodsky et al.
Jian Li et al.
Background: High grade serous ovarian cancer (HGSOC) recurs frequently and commercial tests have emerged for tumor-informed, cell-free DNA (cfDNA)-based detection of minimal residual disease. These tests are based on soma...
Utilization of next generation sequencing from glioma patient liquid biopsy to determine survival prognostics: A systematic review [0.03%]
Christine Sugiarto,Fitri Haryanti,Ibnu Purwanto et al.
Christine Sugiarto et al.
The results of ctDNA measurements generated through the NGS method with liquid biopsy samples show that the higher the grading and sampling when the tumor progresses can increase the ctDNA value.
Combined Real-time Liquid Biopsy with TNM Stage to Guide Induction Chemotherapy Cycles in Nasopharyngeal Carcinoma: A Development and Validation Study [0.03%]
Pengjie Ji,Jiaxi Shen,Danjie He et al.
Pengjie Ji et al.
Purpose: The optimal number of induction chemotherapy (IC) cycles for locally advanced nasopharyngeal carcinoma (LA-NPC) is uncertain. This retrospective study proposes and validates a strategy combining clinical staging ...
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