Liquid biopsy and tissue biopsy for the detection of EGFR mutations in patients with stage III non-small-cell lung cancer: an observational real-world study [0.03%]
U Malapelle,F Nasirova,A Wang et al.
U Malapelle et al.
In non-metastatic disease, the utility of liquid biopsy is less clear....This retrospective observational study assessed the effectiveness of liquid biopsy to detect epidermal growth factor receptor (EGFR) mutations in stage IIIA/IIIB/IIIC NSCLC against tissue biopsy....For all EGFR mutation testing methods, median time between specimen collection and test result availability was 8 days for liquid biopsy (n = 494) and 32 days for tissue biopsy (n = 499); 25 (5%) and 41 (8%) samples, respectively, detected EGFR mutations....Specificity and sensitivity of liquid biopsy were 98% and 45%, respectively. Next-generation sequencing (NGS) was the most common biopsy testing method (liquid, 74%; tissue, 67%)....Further research is warranted to confirm the utility of liquid biopsy for these patients.
Yilong Xing,Shengnan Liu,Xiangshan Yang et al.
Yilong Xing et al.
It is expected that the new THPP/PEI assemblies in this work has potential to be applied to liquid biopsy technology because of their portability and cost effectiveness.
Hyunji Kim,Byoung Mok Kim,Jinho Kim et al.
Hyunji Kim et al.
Background/aim: Circulating tumor DNA (ctDNA) testing has emerged as a minimally invasive tool for precision oncology, enabling dynamic monitoring of tumor burden and treatment response. However, commercial ctDNA NGS assa...
Benedikt Schmidl,Keyang Wei,Narges Ghasemimehr et al.
Benedikt Schmidl et al.
Tumor-educated platelets (TEPs) have emerged as promising biomarkers for cancer detection, monitoring, and therapeutic evaluation. Unlike traditional tissue biopsies, liquid biopsies leveraging TEPs offer a non-invasive approach to overcome...
Microscale Inertial Flow Enables Direct Separation of Nanoscale Extracellular Vesicles from Whole Blood for Gastric Cancer Proteomic Analysis [0.03%]
Haibin Si,Dexin Du,Chengcheng Jiao et al.
Haibin Si et al.
This strategy combines the specificity of immunocapture with the efficiency of inertial microfluidics, offering great potential for advancing EV-based liquid biopsy and precision medicine applications.
Interlaced roles of mitochondrial DNA in colorectal cancer: Liquid-biopsy biomarkers, nuclear mtDNA-driven genomic instability, and mito-encoded micro peptide signaling [0.03%]
Thai-Hau Koo,Xue-Bin Leong,Yi-Lin Lee et al.
Thai-Hau Koo et al.
Colorectal cancer (CRC) is a widely occurring malignancy with significant mortality on a global scale, making up close to 10% of all diagnosed cancers in 2020. While traditional CRC diagnostics and research have focused on nuclear genomic a...
Joe Youssef,Amani Yehya,Zahraa Salhab et al.
Joe Youssef et al.
Among these, liquid biopsy (LB) technology has evolved during the past few years and offers emerging and novel modalities in the field of oncology.
Zhuo Wang,Qihui Shi
Zhuo Wang
Single-cell whole genome sequencing (WGS) enables accurate identification and characterize circulating tumor cells (CTCs) in blood and non-blood body fluids, leading to a non- or minimally invasive liquid biopsy approach for cancer diagnosis and prognosis.
Covalent organic framework-based electrochemical nanosensing: an emerging paradigm for early cancer diagnosis and longitudinal surveillance [0.03%]
基于共价有机框架的电化学纳米传感：一种新兴的癌症早期诊断和长期监测范式
Yue Zhang,Shuyi Chen,Jie Ma et al.
Yue Zhang et al.
Real-time analysis of tumor markers within the tumor microenvironment via liquid biopsy opens potential pathways for effective cancer treatment and improved survival rates....Recent advances in COF-based electrochemical sensors for liquid biopsy are summarized here, with details on COF design principles, synthesis and functionalization methods, and electrochemical reaction mechanisms.
Fluid biopsies for in vitro fertilization: Non-invasive innovations (Review) [0.03%]
试管婴儿的液体活检：非侵入性创新（综述）
Senem Aslan Öztürk,Nergis Özlem Kiliç,Duygu Kütük et al.
Senem Aslan Öztürk et al.
The present review aimed to summarize and critically evaluate developments in non-invasive liquid biopsy techniques in IVF, highlight their clinical applications for improving IVF outcomes, and examine the molecular profile of granulosa and cumulus cells as determinants of oocyte and embryo quality.
耗时 0.08796 秒，为您在
49186863
条记录里面共找到 6531 篇文章 [XML]