Downregulated lysyl oxidase in plasma extracellular vesicles: a biomarker linked to brain metastasis risk in lung adenocarcinoma [0.03%]
Jing Li,Yu Pei,Jia-Li Sun et al.
Jing Li et al.
Extracellular vesicles (EVs), which carry bioactive molecules, play a critical role in tumor microenvironment remodeling and exhibit metastatic organotropism, holding promise as liquid biopsy biomarkers.
DNA-junction-based personalized liquid biopsy assays could inform management of aggressive endometrial cancer [0.03%]
Faye R Harris,Luigi A De Vitis,Leah Grcevich et al.
Faye R Harris et al.
Objective: We investigated the clinical validity and feasibility of a DNA junction-based quantitative polymerase chain reaction assay to detect and quantitate circulating tumor DNA (ctDNA) in the blood of high-risk patien...
Extracellular vesicles released in vitro from a Parkinson's disease-like model: a combined biochemical and spectroscopic approach as proof of concept for the diagnosis of neurodegenerative diseases [0.03%]
体外帕金森病模型释放的细胞外囊泡：作为概念验证用于神经退行性疾病诊断的生化和光谱方法的结合
Sabrina Romanò,David Becerril Rodriguez,Amanda Spahiu et al.
Sabrina Romanò et al.
As proof of concept, our findings highlight the diagnostic and non-invasive potential of these biomarkers for distinguishing pathology, supporting their possible use in liquid biopsy for neurodegenerative diseases.
A boronate affinity-enhanced and PEGylated cell-imprinted platform for efficient capture of circulating colorectal cancer cells [0.03%]
一种硼亲和力增强型和PEG修饰的印迹平台，可有效捕获循环结直肠癌细胞
Yang Yu,Qinchen An,Zichang Song et al.
Yang Yu et al.
This platform addressed key limitations of current technologies by combining specific capture, minimal non-specific adsorption and gentle cell release, offering a promising tool for advancing liquid biopsy in CRC diagnosis and monitoring.
Comparative Liquid Biopsy Testing for KRAS Mutations From Plasma Cell-Free DNA (cfDNA) and Extracellular Vesicles in Lung Adenocarcinoma [0.03%]
比较分析肺癌肺腺癌患者血浆游离DNA和外泌体中KRAS突变的液体活检检测结果
Caeli J Zahra,Tian Mun Chee,Edward K H Stephens et al.
Caeli J Zahra et al.
Extracellular vesicles (EVs) are secreted into biofluids to transport cargo such as DNA and are a potential biosource for liquid biopsy biomarkers....To determine the optimal use of liquid biopsy for diagnosing mutations in lung adenocarcinoma (LUAD), we compared the KRAS mutation status in DNA isolated from four different plasma fractions, including EVs.
Comparative Study
Cancer reports (Hoboken, N.J.). 2026 Mar;9(3):e70517. DOI:10.1002/cnr2.70517 2026
OncoCan: a liquid biopsy assay for cell-free DNA quantification in canine plasma to support cancer prognosis [0.03%]
OncoCan：一种用于犬血浆中游离DNA定量的液体活检方法，以支持癌症预后判断
Sánchez Virginia,Farreny Gal la,Martinez-Merlo Elena et al.
Sánchez Virginia et al.
Cell-free DNA (cfDNA), released into the bloodstream through apoptosis, necrosis, or circulating tumor cells, can be quantified non-invasively via liquid biopsy and is already established in human oncology.
Harnessing the immune microenvironment: advances in nasopharyngeal carcinoma immunotherapy [0.03%]
利用免疫微环境：鼻咽癌免疫治疗的新进展
Yihua Zhu,Yongsheng Liu,Zhikang Yin et al.
Yihua Zhu et al.
Biomarker advances extend beyond PD-L1 to include radiomics, AI-driven models, liquid biopsy markers (EBV-DNA dynamics, exosomal CA1), and tissue-based features (tertiary lymphoid structures, CD70/CD27 axis).
Epitranscriptomic signatures of malignancy: how RNA modifications shape breast and ovarian tumor progression [0.03%]
表观转录组标志在恶性肿瘤中的作用：RNA修饰如何影响乳腺癌和卵巢癌的发展进展
Pankaj Garg,Ravi Salgia,Sharad S Singhal
Pankaj Garg
In addition, RNA modification patterns are emerging as promising diagnostic and prognostic biomarkers, with growing applications in liquid biopsy and precision oncology.
Comprehensive circulating tumor DNA mutation profiling via CAPP-Seq liquid biopsy for cervical cancer [0.03%]
宫颈癌的CAPP-Seq液体活检全面循环肿瘤DNA突变检测Profiler结果分析
Naoyuki Iwahashi,Tomoko Noguchi,Kazuko Sakai et al.
Naoyuki Iwahashi et al.
Background: Liquid biopsy using circulating tumor DNA (ctDNA) is a minimally invasive approach for detecting tumor-associated genomic alterations. Although ctDNA analysis has been widely explored in solid tumors, its appl...
Integrated and Ultrafast Multiomics Sample Preparation Workflow for Screening Biomarker Panel of Platelet Biomolecules for Early Diagnosis of HCC [0.03%]
用于筛查血小板生物分子标志物以实现肝癌早期诊断的集成超快速多组学样品制备流程
Fenglin Shen,Yang Liu,Xuelian Ruan et al.
Fenglin Shen et al.
Owing to its minimal invasiveness, liquid biopsy has emerged as a promising alternative for early screening.
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