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Molecular Encoding during Amplification Enables Multiplex Nanopore Profiling of Small Noncoding RNAs

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Many cancers are characterized by the coordinated dysregulation of multiple small noncoding RNAs (sncRNAs), yet fluorescence-based assays such as quantitative reverse transcription PCR (qRT-PCR) fundamentally limit multiplexing. Here, we report an amplificatio... ...