Neighboring macrophage-induced alteration in the phenotype of colorectal cancer cells in the tumor budding area [0.03%]
肿瘤芽区域巨噬细胞诱导的结肠癌细胞表型变化
Ichiro Kawamura,Rintaro Ohe,Kazushi Suzuki et al.
Ichiro Kawamura et al.
Background: A higher number of tumor buds in the invasive front of colorectal cancer (CRC) specimens has been shown to contribute to a poor prognosis in CRC patients. Because macrophages (Mφs) have been demonstrated to a...
Identification of GSPT1 as prognostic biomarker and promoter of malignant colon cancer cell phenotypes via the GSK-3β/CyclinD1 pathway [0.03%]
GSPT1作为结肠癌预后生物标志物通过GSK-3β/CyclinD1通路促进恶性结肠癌细胞表型识别
Xuan Long,Lijun Zhao,Guoqiang Li et al.
Xuan Long et al.
Colon cancer is the third most common malignant tumor and its mortality rate ranks fourth among all malignant tumor types. Bioinformatics analysis has shown that GSPT1 is dysregulated in colon cancer and is associated with tumor progression...
Modulation of the colon cancer cell phenotype by pro-inflammatory macrophages: A preclinical model of surgery-associated inflammation and tumor recurrence [0.03%]
促炎巨噬细胞对结肠癌细胞表型的调节：与手术相关炎症和肿瘤复发的临床前模型
María Marcuello,Xavier Mayol,Eloísa Felipe-Fumero et al.
María Marcuello et al.
Peritoneal infection after colorectal cancer surgery is associated with a higher rate of tumor relapse. We have recently proposed that soluble inflammatory factors released in response to a postoperative infection enhance tumor progression ...
Role of calcium in E-selectin induced phenotype of T84 colon carcinoma cells [0.03%]
钙在E-选择素诱导结肠癌细胞表型中的作用
M D&#x;Amato,A M Flugy,G Alaimo et al.
M D&#x;Amato et al.
The adhesion of cancer cells to the endothelium during the metastatic process involves the interaction of specific cell-cell adhesion receptors on the cell surface. E-selectin on endothelial cells and sialyl Lewis X carbohydrate component o...
The effects of short-chain fatty acids on human colon cancer cell phenotype are associated with histone hyperacetylation [0.03%]
短链脂肪酸对人类结肠癌细胞表型的影响与组蛋白过度乙酰化相关
Brian F Hinnebusch,Shufen Meng,James T Wu et al.
Brian F Hinnebusch et al.
The short-chain fatty acid (SCFA) butyrate is produced via anaerobic bacterial fermentation within the colon and is thought to be protective in regard to colon carcinogenesis. Although butyrate (C4) is considered the most potent of the SCFA...
Differential modulation of human (Caco-2) colon cancer cell line phenotype by short chain fatty acids [0.03%]
短链脂肪酸通过不同机制调节人类结肠癌细胞系(Caco-2)的表型
M D Basson,N J Emenaker,F Hong
M D Basson
Fermentation of dietary fiber within the colonic lumen yields short chain fatty acids (SCFA) such as butyrate, which may modulate colonic mucosal biology and inhibit the development of a malignant phenotype. However, different fibers yield ...
Regulation of cathepsin D dependent on the phenotype of colon carcinoma cells [0.03%]
结肠癌细胞表型依赖的猫斯贝辛酶D调节机制研究
S Hennebicq Reig,I Kim,A Janin et al.
S Hennebicq Reig et al.
We have studied the intracellular trafficking of cathepsin D in different colon carcinoma cell populations: the HT-29 cell line, composed of >95% undifferentiated cells; 2 subpopulations derived from this cell line, containing cells committ...
Effects of interferons alpha,beta,gamma alone or in combination on the phenotype of human colon carcinoma cells [0.03%]
干扰素α、β、γ对人结肠癌细胞表型的单独及联合作用效应
D Brouty-Boyé,M T Maunoury,R Lowy
D Brouty-Boyé
The ability of interferons (IFNs) alpha,beta,gamma, alone or in combination, to induce reversion of the phenotype of cloned human colon carcinoma cells during long-term treatment was studied. The phenotypic characteristics examined were pro...