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Francisco Willamy Pedrosa Alves Filho,Nágila Alves Lima,Beatriz Ximenes Mendes et al. Francisco Willamy Pedrosa Alves Filho et al.
Background: The common use of proton pump inhibitors (PPIs) and histamine 2 receptor antagonists (H2RA) in critically ill patients may increase the incidence of pneumonia associated with mechanical ventilation caused by alkalinization of ga...
Li-Juan Yang,Fang Yu,Yu Chen et al. Li-Juan Yang et al.
Background: Recent studies showed histamine H2 receptor antagonists (H2RAs) exposure was associated with reduced mortality in heart failure (HF) patients. However, specific HF patients who are sensitive to H2RAs exposure ...
Dongdong Zhang,Ying Cai,Yixin Sun et al. Dongdong Zhang et al.
Famotidine is an H2 receptor antagonist and is currently used on a large scale in gastroenterology. However, Famotidine may also cause severe toxicity to organ systems, including the blood system, digestive system, and urinary system. The o...
Dan Wang,Hailan Chen,Yunhao Luo Dan Wang
Despite advancements in the treatment of heart failure (HF) and modest improvements in survival rates over the past few decades, mortality rate remains significantly high. HF not only imposes a significant economic burden on patients' famil...
Mustafa Eray Kilic,Mehmet Birhan Yilmaz Mustafa Eray Kilic
Purpose: The management of heart failure (HF) frequently includes gastroprotection via proton pump inhibitors (PPIs) or histamine-2 receptor antagonists (H2RAs). This systematic review evaluates their impact on HF outcome...
Jian-Mei Pan,Yu Guo,Fang-Fang Jiang et al. Jian-Mei Pan et al.
Previous studies found that histamine H2 receptor antagonists (H2RAs) had blood pressure lowering and cardioprotective effects, but the impact of H2RAs on the survival outcomes of critically ill patients with essential hypertension is still...
Kasper B Assersen,Boye L Jensen,Camilla Enggaard et al. Kasper B Assersen et al.
Aldosterone through the mineralocorticoid receptor MR has detrimental effects on cardiovascular disease. It reduces the bioavailability of nitric oxide and impairs endothelium-dependent vasodilatation. In resistance arteries, aldosterone im...
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