Strontium-Containing Bioactive Glass Nanoparticles Stimulate Osteogenesis and Suppress Osteoclast Formation in Co-Culture [0.03%]
含锶生物活性玻璃纳米颗粒刺激成骨并抑制共培养中的破骨细胞形成
Parichart Naruphontjirakul,Alexandra E Porter,Julian R Jones
Parichart Naruphontjirakul
The effect of monodispersed bioactive glass nanoparticles containing strontium (9.4 mol % SrO and 4.4 mol% SrO) and their dissolution products on osteoclast differentiation are investigated in monoculture and in an osteoblast-osteoclast in ...
Porphyran Inhibits Osteoclast Formation Based on NF-κB Signaling Pathways and Accelerates Alveolar Bone Healing in Ovariectomized Mice [0.03%]
_porphyran通过NF-кB信号通路抑制破骨细胞形成并促进卵巢切除小鼠牙槽骨愈合
Pei Wu,Yizhou Wang,Sijing Chu et al.
Pei Wu et al.
Osteoporosis is characterized by a disrupted bone remodeling process, with bone resorption exceeding bone formation, resulting in reduced bone mass and impaired bone defect healing. Porphyran (PYP), a sulfated polysaccharide extracted from ...
Gallic acid released by a layered double hydroxide-coated scaffold of hydroxyapatite and β-tricalcium phosphate inhibits the osteoclast formation In Vitro [0.03%]
层状双氢氧化物包覆的羟基磷灰石和β-三磷酸钙支架释放出的没食子酸体外抑制破骨细胞形成
Chiara Suvieri,Maria Bastianini,Stefano Pagano et al.
Chiara Suvieri et al.
Following dental extraction, alveolar bone loss, driven by the osteoclast (OC) bone-eroding cells, is a relevant concern in dental practice since it could compromise the possibility of installing dental implants. This study aimed to develop...
Anti-resorptive dihydrophenanthrene coelonin alleviates arthritic bone destruction by inhibiting osteoclast formation and synovial inflammation through Src regulation [0.03%]
(src调控抑制破骨细胞形成和滑膜炎症抗吸收二氢菲类化合物秋水仙碱可缓解关节炎性骨破坏作用研究)
Yanbei Tu,Wendi Yue,Guiyu Dai et al.
Yanbei Tu et al.
Background: The overactivation of osteoclasts (OCs) and fibroblast-like synoviocytes (FLS) is a key contributor to the bone destruction associated with rheumatoid arthritis (RA). Coelonin (COE) is known as an anti-inflamm...
High glutamate levels in the bone marrow of multiple myeloma patients promote osteoclast formation: a novel target for osteolytic bone disease [0.03%]
多发性骨髓瘤患者骨髓中高谷氨酸水平促进破骨细胞的形成：骨溶解性骨病的新靶点
Denise Toscani,Oxana Lungu,Martina Chiu et al.
Denise Toscani et al.
Multiple Myeloma (MM) is a glutamine (Gln)-addicted cancer. Consequently, the MM bone microenvironment (BM) is characterized by lower Gln and higher glutamate (Glu) levels than those in pre-malignant monoclonal gammopathies. Such MM-depende...
Dodecylmethylaminoethyl methacrylate inhibits the growth of Candida albicans and Enterococcus faecalis biofilm and the formation of osteoclast [0.03%]
十二烷基甲基氨基乙基丙烯酸酯抑制白色念珠菌和粪肠球菌生物膜的生长及破骨细胞形成
Zong Yawen,Shan Tiantian,Shi Yangyang et al.
Zong Yawen et al.
Objectives: This study aimed to evaluate the antimicrobial ability on the dual-species biofilm formed by C. albicans and E. faecalis and osteoclysis inhibition of DMAEM. ...
Bone marrow neutrophil progenitors suppress osteoclast formation in murine cortical and trabecular bone [0.03%]
骨髓粒细胞祖细胞在小鼠皮质骨和小梁骨中抑制破骨细胞形成
Tsuyoshi Isojima,Blessing Crimeen-Irwin,Narelle E McGregor et al.
Tsuyoshi Isojima et al.
In inflammation, circulating neutrophils indirectly damage the skeleton by inducing formation of bone-resorbing osteoclasts. However, neutrophil progenitors in marrow have no known physiological function. A bone-protective role for the neut...
A naturally occurring phenanthrene from Pleione bulbocodioides inhibits osteoclast formation by directly targeting Src kinase [0.03%]
pleione素通过直接靶向Src激酶抑制破骨细胞形成
Ying Yang,Lin Li,Dehong Yu et al.
Ying Yang et al.
Elevated bone resorption resulting from osteoclast (OC) overactivation is a primary factor contributing to osteoporosis progression, suggesting plant-derived antiresorptive agents targeting osteoclast formation and function are effective st...
Osteoclast formation in the co-presence of octacalcium phosphate and inorganic phosphorus-containing gelatin in vitro [0.03%]
八钙磷酸盐和无机磷化明胶共存时的破骨细胞体外形成
Ryo Hamai,Kenya Tomitsuka,Masahiro Okada et al.
Ryo Hamai et al.
This study was designed to investigate the effect of biodegradable octacalcium phosphate (OCP) bone substitute on osteoclast formation under the higher inorganic phosphorus concentration in vitro. We developed the gelatin particles releasin...
Human osteoblast response to uncemented knee implant surface structures and osteoclast formation in vitro [0.03%]
人骨细胞对膝关节假体表面结构的响应及破骨细胞的形成
Raymond Puijk,Behrouz Zandieh-Doulabi,Wendy J A M Runderkamp et al.
Raymond Puijk et al.
Early bone ingrowth and minimal resorption ensure rigid fixation in uncemented total knee replacements. Trabecular titanium-aluminum-vanadium (Ti6Al4V) and hydroxyapatite (HA)-coated vacuum-plasma-sprayed (VPS) titanium with varying porosit...
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