Anti-resorptive dihydrophenanthrene coelonin alleviates arthritic bone destruction by inhibiting osteoclast formation and synovial inflammation through Src regulation
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Background: The overactivation of osteoclasts (OCs) and fibroblast-like synoviocytes (FLS) is a key contributor to the bone destruction associated with rheumatoid arthritis (RA). Coelonin (COE) is known as an anti-inflammatory di... ...
