THE STIMULATING EFFECT OF THIENOPYRIMIDINES, THE STRUCTURAL ANALOGS OF ORG 43553, ON THE ACTIVITY OF ADENYLYL CYCLASE IN THE TESTES AND ON THE TESTOSTERONE PRODUCTION IN MALE RATS [0.03%]
关于Org 43553的结构类似物噻嗯并吡啶对雄性大鼠睾丸腺苷酸环化酶活性及促黄体生成激素分泌和雄激素生成的刺激作用
K V Derkach,A S Legkodukh,D V Dar’in et al.
K V Derkach et al.
The regulation of the functional activity of luteinizing hormone (LH) receptor can be carried out by using gonadotropins or low-molecular weight agonists of this receptor, which, unlike gonadotropins, bind to an allosteric site located in t...
[The influence of two-month treatment with bromocryptine on activity of the adenylyl cyclase signaling system in the myocardium and testes of rats with type 2 diabetes mellitus] [0.03%]
溴隐亭治疗对2型糖尿病大鼠心肌和睾丸腺苷酸环化酶信号系统活性的影响
K V Derkach,V M Bondareva,I V Moyseyuk et al.
K V Derkach et al.
One of the common complications of type 2 diabetes mellitus (DM2) are cardiovascular diseases and dysfunctions of the reproductive system, indicating the urgency of developing new approaches to their correction. Last years for the treatment...
[Regulation of adenylyl cyclase activity in the rat testes by acylated derivatives of peptide 562-572 of luteinizing hormone receptor] [0.03%]
黄体生成素受体562-572肽段的酰化衍生物对大鼠睾丸腺苷酸环化酶活性的调节作用
E A Shpakova,A O Shpakov
E A Shpakova
One of directions of the search of hormonal signaling systems regulators is the development of peptides that correspond to the cytoplasmic regions of G-protein-coupled receptors (GPCR). Modification of the pepti- des with hydrophobic radica...
The stimulating influence of thienopyrimidine compounds on the adenylyl cyclase signaling systems in the rat testes [0.03%]
关于嘌呤并嘧啶类化合物刺激大鼠睾丸腺苷酸环化酶信号系统的影响作用
A O Shpakov,D V Dar&#x;in,K V Derkach et al.
A O Shpakov et al.
The functional activity of adenylyl cyclase signaling system in the brain, myocardium, and testes of rats with 8- and 18-month neonatal diabetes [0.03%]
新生糖尿病大鼠脑、心和睾丸腺苷酸环化酶信号系统的功能活性研究
K V Derkach,A O Shpakov,I V Moyseuk et al.
K V Derkach et al.
Decrease of pituitary adenylate cyclase activating polypeptide and its type I receptor mRNAs in rat testes by ethanol exposure [0.03%]
乙醇暴露降低大鼠睾丸腺苷酸环化酶激活多肽及其I型受体的mRNA表达
Phil-Ok Koh,Chung-Kil Won
Phil-Ok Koh
The present study was designed to evaluate the effect of ethanol on pituitary adenylate cyclase activating polypeptide (PACAP) and its typ I (PAC1) receptor expression in adult rat testes. Ethanol (3 g/kg i.p., 15% v/v in saline) was admini...
Effect of hypophysectomy on pituitary adenylate cyclase-activating polypeptide gene expression in the rat testis [0.03%]
低垂体对大鼠睾丸腺苷酸环化酶激活多肽基因表达的影响
Y Shuto,A Somogyvári-Vigh,S Shioda et al.
Y Shuto et al.
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a member of the secretin/glucagon/vasoactive intestinal peptide (VIP) family. Our immunohistochemical and in situ hybridization histochemical studies indicated that PACAP-like im...
Association of triiodothyronine binding activity to soluble adenylate cyclase in testicular preparations [0.03%]
甲状腺素结合活性与睾丸腺苷酸环化酶的可溶性部分的关系研究
A R Kornblihtt,M M Flawiá,D de Mendoza et al.
A R Kornblihtt et al.
Cytosolic adenylate cyclase activity from rat seminiferous tubules was purified by chromtography in DEAE-cellulose, hydroxylapatite and Bio-Gel A-0.5 m as well as by centrifugation in sucrose gradients. In all these purification steps, frac...
Activation of adenylate cyclase by forskolin in rat brain and testis [0.03%]
姜黄素激活剂 Forskolin 对大鼠脑及睾丸腺苷酸环化酶的活化作用
M Sano,S Kitajima,A Mizutani
M Sano
Detergent-dispersed adenylate cyclase from rat cerebrum was detected in two components, one sensitive to Ca2+ and calmodulin and another sensitive to fluoride or guanyl-5'-yl imidodiphosphate (Gpp(NH)p). The enzyme activity of both componen...
Demonstration of distinct forms of testicular adenylate cyclases associated with germinal and Leydig cell fractions [0.03%]
不同形式的睾丸腺苷酸环化酶的相关实验验证（与生殖细胞和Leydig细胞组分有关）
T D Noland,M H Melner,D Puett
T D Noland
Decapsulated testes from adult rats were digested with collagenase, and the fraction enriched in germinal and Leydig cells was applied to a 0-4% continuous metrizamide gradient and centrifuged. This leads to separation of a germinal cell fr...
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