A sex-specific Mendelian randomization-phenome-wide association study of body mass index [0.03%]
基于体质指数的孟德尔随机化-表型组关联研究的性别差异
Zhu Liduzi Jiesisibieke,Io Ieong Chan,Jack Chun Man Ng et al.
Zhu Liduzi Jiesisibieke et al.
Background: Trials of incretins are making it increasingly clear that body mass index (BMI) is linked to several diseases throughout life, but trials cannot easily provide a comprehensive assessment of the role of BMI in ...
Lipoprotein(a) and its linear association with all-cause and cardiovascular mortality in patients with acute coronary syndrome [0.03%]
急性冠脉综合征患者脂蛋白(a)与全因及心血管死亡的线性关联研究
Ke Qin,Tingyuan Zhang
Ke Qin
Objective: This study aimed to investigate the linear association between lipoprotein(a) [Lp(a)] levels and all-cause and cardiovascular mortality in patients with acute coronary syndrome (ACS). ...
The Association Between Marijuana Use and Myocardial Infarction, Asthma, and Depression in Racial and Sexual Minorities: BRFSS 2016-2022 [0.03%]
2016至2022年美国行为危险因素 surveillance系统调查数据中少数族裔和性少数群体大麻使用与心肌梗死、哮喘及抑郁的关联研究
Heather R Willmott,Sixia Chen
Heather R Willmott
Introduction: Marijuana-use patterns differ among racial and sexual minority groups, but few studies have examined health effects in these subgroups. The authors aimed to study the relationship between marijuana use and h...
Associations between Aβ deposition and neurometabolic alterations in Alzheimer's disease: Insights from hybrid 3D MRSI-PET imaging [0.03%]
基于混合三维MRSI-PET成像的阿尔茨海默病患者脑内淀粉样蛋白沉积与神经元代谢改变之间的关联研究
Miao Zhang,Jialin Hu,Yaoyu Zhang et al.
Miao Zhang et al.
Introduction: Understanding the neurometabolic changes associated with amyloid-β (Aβ) deposition is important for early Alzheimer's disease (AD) diagnosis, but their spatial relationships remained unexplored due to tech...
GWAS links APOE to neuropsychiatric symptoms in mild cognitive impairment and dementia [0.03%]
通过GWAS链接APOE与轻度认知障碍和痴呆的神经精神症状的关系
Selina M Vattathil,Freida Blostein,Tyne W Miller-Fleming et al.
Selina M Vattathil et al.
Introduction: Neuropsychiatric symptoms in dementia (NPS) collectively refer to behavioral and psychological symptoms affecting individuals with mild cognitive impairment (MCI) or Alzheimer's disease or related dementia (...
Discovering leaf and stripe rust resistance in soft red winter wheat through genome-wide association studies [0.03%]
通过全基因组关联分析在软红冬小麦中发掘小叶病和条锈病抗性基因
John W Bagwell,Mohamed Mergoum,Madhav Subedi et al.
John W Bagwell et al.
Leaf rust (LR) and stripe rust (YR), which are caused by Puccinia triticina and Puccinia striiformis, respectively, are among the most devastating wheat rusts worldwide. These diseases can be managed by using genetically resistant cultivars...
Epigenome-wide association study of cerebrospinal fluid-based biomarkers of Alzheimer's disease in cognitively normal individuals [0.03%]
基于脑脊液生物标志物的表观基因组关联研究在认知正常的个体中的阿尔茨海默病
Anke Hüls,Jiaqi Liu,Chaini Konwar et al.
Anke Hüls et al.
Introduction: Cerebrospinal fluid (CSF) biomarkers of Alzheimer's disease (AD) are reliable predictors of future AD risk. We investigated whether pre-clinical changes in AD CSF biomarkers are reflected in blood DNA methyl...
Meta-analysis of uveal melanoma genome-wide association studies identifies novel risk loci and population effect size heterogeneity [0.03%]
全身基因组关联研究的 meta 分析鉴定葡萄膜黑色素瘤的新易感位点及不同人群效应值异质性
Georgia Mies,Noah L Tsao,Alexandre Houy et al.
Georgia Mies et al.
Uveal melanoma (UM) is a rare but frequently metastasizing cancer. Genome-wide association studies have identified three common genome-wide significant germline risk loci. Here, we perform a genome-wide association study on 401 new cases an...
Integrative multi-omics investigation of sleep apnea: gut microbiome metabolomics, proteomics and phenome-wide association study [0.03%]
睡眠呼吸暂停的整合多组学研究：肠道微生物、代谢组、蛋白质组和表型广泛关联研究
Shuxu Wei,Ronghuai Shen,Xiaojia Lu et al.
Shuxu Wei et al.
Background: Sleep apnea (SA) is linked to various diseases. This study examines the causal link between the gut microbiome and SA, exploring potential predictive factors and target proteins using a multi-omics approach wi...
The association between PSCA gene polymorphism and hepatocellular carcinoma risk [0.03%]
PSCA基因多态性与肝癌风险的关联研究
Xiechen Wang,Xiaoqiang Sun,Xuyin Wang et al.
Xiechen Wang et al.
Background: The current study aims to determine whether prostate stem cell antigen (PSCA) gene polymorphism confers a risk for hepatocellular carcinoma (HCC). The aim is to find out the novel markers for predicting HCC ri...
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