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Review Human pathology. 2025 Jun 11:105835. doi: 10.1016/j.humpath.2025.105835 Q22.62025

Prognostic Models for Breast Cancer: A Narrative Review

乳腺癌预后模型的叙事综述 翻译改进

Hua Guo  1, Shi Wei  2

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作者单位

  • 1 Department of Pathology and O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL 35233.
  • 2 Department of Pathology and O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL 35233; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL 35233. Electronic address: swei@uabmc.edu.
  • DOI: 10.1016/j.humpath.2025.105835 PMID: 40513962

    摘要 中英对照阅读

    Cancer prognostic models use a combination of risk factors to estimate the probability of patients' clinical outcomes, allowing the physicians to categorize patients into risk groups to guide clinical decision making. An ideal prognostic model would accurately predict patient survival and/or recurrence risk, taking into account a combination of clinical and pathological parameters that are readily available in the standard of care practice, thus can be wi... ...点击完成人机验证后继续浏览

    癌症预后模型通过结合风险因素来估计患者的临床结局概率,使医生能够将患者分类为不同的风险组以指导临床决策。理想的预后模型应该能准确预测患者的生存率和/或复发风险,并考虑标准诊疗实践中可获得的临床和病理参数组合,从而可以广泛使用并持续校准。迄今为止,已经提出了许多乳腺癌预后模型。这些模型在开发和验证方法、预测因素组成、预期临床结局及其应用方面各不相同。预后因子的识别很大程度上依赖于对肿瘤病理特征的准确评估,而这又取决于病理学家的作用。因此,在病理实践中理解预后模型对于提供更准确和个性化的患者护理至关重要。本文综述了临床上常用的乳腺癌预后模型。

    关键词: 乳腺癌;基因组检测;新辅助治疗;预后模型;复发;生存。

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    期刊名:Human pathology

    缩写:HUM PATHOL

    ISSN:0046-8177

    e-ISSN:1532-8392

    IF/分区:2.6/Q2

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