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Trials. 2025 Jun 5;26(1):199. doi: 10.1186/s13063-025-08804-y Q32.02024

Teletrial implementation in early phase clinical trials: two national workshops

远程试验在早期临床试验中的实施应用——两次全国研讨会的经验总结 翻译改进

Jessica Freeman  1, Craig Underhill  2  3  4, William Evans  5, Donna Long  3, Sam Harris  6, Kate Burbury  2  7, Anne Woollett  5, Mark Buzza  2

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作者单位

  • 1 Victorian Comprehensive Cancer Centre Alliance, Parkville, VIC, Australia. jessefreeman.23@gmail.com.
  • 2 Victorian Comprehensive Cancer Centre Alliance, Parkville, VIC, Australia.
  • 3 Border Medical Oncology Research Unit, Albury Wodonga Regional Cancer Centre, Albury, NSW, Australia.
  • 4 University of NSW Rural Medical School, Albury, NSW, Australia.
  • 5 TrialHub Alfred, 55 Commercial Rd, Prahran, Melbourne, VIC, 3004, Australia.
  • 6 Bendigo Health, Bendigo, VIC, Australia.
  • 7 Department of Haematology, Peter MacCallum Cancer Centre & Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia.
  • DOI: 10.1186/s13063-025-08804-y PMID: 40474272

    摘要 中英对照阅读

    Teletrials aim to improve equity of access to clinical trials and increase clinical trial activity, especially for people with cancer in regional and rural communities. Three cancer programs, using a collective impact framework, form the Victorian Teletrial Collaborative (VTC) to enhance the uptake of teletrials. The VTC conducted two workshops with a focus on early-phase clinical trials with national stakeholders; the collaborative was able to clarify various perspectives regarding the barriers and enablers to the implementation of the teletrial model for use in early-phase clinical trials. The first workshop identified a range of barriers and enablers, while the second workshop explored the specificity of these insights to early phase teletrials. It was concluded that the identified barriers were generic to all trials utilising the teletrial model, multicentre trials early phase trials more generally. An action plan addressing six key themes has been developed to support the coordination of a national effort to progress trial activity in early phase teletrials.

    Keywords: Clinical trials; Decentralised clinical trials; Early phase trials; Teletrials; Trial methodology; Workshop.

    Keywords:teletrial implementation; clinical trials; national workshops

    远程临床试验旨在提高偏远和农村社区癌症患者参与临床试验的公平性,并增加临床试验活动。三个癌症项目使用集体影响框架,组成了维多利亚远程临床试验协作组织(VTC),以增强远程临床试验的采用率。VTC举办了两次专注于早期阶段临床试验并与全国利益相关者合作的工作坊;该协作组织能够澄清有关实施远程临床试验模型用于早期阶段临床试验的各种观点和障碍。第一次研讨会确定了一系列障碍和促进因素,而第二次研讨会则探讨了这些见解在早期阶段远程临床试验中的具体性。结论认为,所识别的障碍适用于所有使用远程临床试验模式的试验,包括多中心试验和一般意义上的早期阶段临床试验。已制定了一份涵盖六个关键主题的行动计划,以支持协调全国范围内的努力,推动早期阶段远程临床试验活动。

    关键词:临床试验;分散式临床试验;早期阶段试验;远程临床试验;试验方法;研讨会。

    关键词:远程试验实施; 临床试验; 国家研讨会

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