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International journal of health sciences. 2025 Mar-Apr;19(2):17-25. Q22.12025

Zingerone mitigates metabolic dysfunction and alters pro-opiomelanocortin gene expression in offspring of high-fat diet-fed pregnant wistar rats

姜根醇可以改善高脂饮食喂养的孕大鼠后代出现的新陈代谢功能紊乱,并改变促黑色素细胞激素基因表达 翻译改进

Deborah Boluwatife Adeniyi  1, Nkiru Amala Katchy  1, Chidera Sandra James-Edeh  1, Chioma Marylyn Adilieje  2, David Chibuike Ikwuka  3, Amechi Uche Katchy  4, Elvis Shu  5, Bond Ugochukwu Anyaehie  1

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作者单位

  • 1 Department of Physiology, Faculty of Basic Medical Sciences, University of Nigeria, Enugu Campus, Nigeria.
  • 2 Department of Medical Biochemistry, Faculty of Basic Medical Sciences, University of Nigeria, Enugu Campus, Nigeria.
  • 3 Department of Medical Physiology, School of Medicine and Pharmacy, College of Medicine and Health Sciences, University of Rwanda, Rwanda.
  • 4 Department of Anatomy, Faculty of Basic Medical Sciences, University of Nigeria, Enugu Campus, Nigeria.
  • 5 Department of Pharmacology, Faculty of Basic Clinical Science, University of Nigeria, Enugu Campus, Nigeria.
  • PMID: 40046792

    摘要 Ai翻译

    Objectives: In utero, exposure to maternal high-fat diet (HFD) has been identified to predispose the offspring to obesity and other metabolic dysfunctions later in life. Zingerone, a bioactive phytochemical found in ginger has potential for the treatment of metabolic diseases due to its antioxidant properties. This study investigated its potential reprogramming effect on some metabolic indices and pro-opiomelanocortin (POMC) ... ...点击完成人机验证后继续浏览
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    期刊名:International journal of health sciences-ijhs

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    ISSN:1658-3639

    e-ISSN:1658-7774

    IF/分区:2.1/Q2

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    Zingerone mitigates metabolic dysfunction and alters pro-opiomelanocortin gene expression in offspring of high-fat diet-fed pregnant wistar rats