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Review Annual review of cell and developmental biology. 2024 Jul 9. doi: 10.1146/annurev-cellbio-111822-010628 Q111.42024

Left-Right Asymmetry in Invertebrates: From Molecules to Organisms

无脊椎动物的左右不对称性:从分子到个体 翻译改进

Reiko Kuroda  1  2

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  • 1 1Frontier Research Institute, Chubu University, Kasugai, Japan; email: rkuroda@isc.chubu.ac.jp.
  • 2 2International Institute for Sustainability with Knotted Chiral Meta Matter (SKCM2), World Premier International Research Center Initiative (WPI), Hiroshima University, Hiroshima, Japan.
  • DOI: 10.1146/annurev-cellbio-111822-010628 PMID: 38985858

    摘要 Ai翻译

    Although most animals appear symmetric externally, they exhibit chirality within their body cavity, i.e., in terms of asymmetric organ position, directional organ looping, and lateralized organ function. Left-right (LR) asymmetry is determined genetically by intricate molecular interactions that occur during development. Key genes have been elucidated in several species. There are common mechanisms in vertebrates and invertebrates, but some appear to exhibit unique mechanisms. This review focuses on LR asymmetry formation in invertebrates, particularly Drosophila, ascidians, and mollusks. It aims to understand the role of the genes that are key to creating LR asymmetry and how chirality information is converted/transmitted across the hierarchies from molecules to cells and from cells to tissues.

    Keywords:left-right asymmetry; invertebrates; molecules; organisms

    Copyright © Annual review of cell and developmental biology. 中文内容为AI机器翻译,仅供参考!

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    期刊名:Annual review of cell and developmental biology

    缩写:ANNU REV CELL DEV BI

    ISSN:1081-0706

    e-ISSN:1530-8995

    IF/分区:11.4/Q1

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    Left-Right Asymmetry in Invertebrates: From Molecules to Organisms