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The Journal of antibiotics. 2024 Jun;77(6):338-344. doi: 10.1038/s41429-024-00720-8 Q22.72025

Three new phthalide derivatives from culture broth of Dentipellis fragilis and their cytotoxic activities

三种来自齿孔薄革菌培养物的新的酞衍生物及其细胞毒性作用 翻译改进

Dae-Won Ki  1, Dae-Cheol Choi  2, Yeong-Seon Won  3  4, Seung-Jae Lee  3  5, Young-Hee Kim  2, In-Kyoung Lee  2, Bong-Sik Yun  6

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作者单位

  • 1 Division of Biotechnology and Advanced Institute of Environment and Bioscience, College of Environmental and Bioresource Sciences, Jeonbuk National University, Iksan-si, 54596, Korea. dwki0916@gmail.com.
  • 2 Division of Biotechnology and Advanced Institute of Environment and Bioscience, College of Environmental and Bioresource Sciences, Jeonbuk National University, Iksan-si, 54596, Korea.
  • 3 Functional Biomaterial Research Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup, 56212, Korea.
  • 4 Division of Research Management, Department of Bioresource Industrialization, Honam National Institute of Biological Resource, Mokpo, 58762, Republic of Korea.
  • 5 Department of Applied Biotechnology, University of Science and Technology (UST), Daejeon, 34113, Korea.
  • 6 Division of Biotechnology and Advanced Institute of Environment and Bioscience, College of Environmental and Bioresource Sciences, Jeonbuk National University, Iksan-si, 54596, Korea. bsyun@jbnu.ac.kr.

    • DOI: 10.1038/s41429-024-00720-8 PMID: 38519550

    摘要 Ai翻译

    Three new phthalide derivatives (1‒3) together with two known compounds, erinaceolactone B (4) and hericerin III (5), were isolated from the culture broth of Dentipellis fragilis. The chemical structures of 1‒5 were determined by analyses of their 1D-, 2D-NMR, and MS. The absolute configuration of 1 was determined by CD analysis. The isolated compounds were assessed for their cytotoxic activities against A549, DU145, HCT116, and HT1080 cancer cell lines.... ...点击完成人机验证后继续浏览
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    期刊名：Journal of antibiotics

    缩写：J ANTIBIOT

    ISSN：0021-8820

    e-ISSN：1881-1469

    IF/分区：2.7/Q2

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    Three new phthalide derivatives from culture broth of Dentipellis fragilis and their cytotoxic activities