The Journal of antibiotics. 2024 Apr;77(4):206-213. doi: 10.1038/s41429-023-00699-8 Q22.72025
Virgaricins C and D, new pramanicin analogs produced by Apiospora sp. FKI-8058
由FKI-8058 Apiospora产生新的pramanicin类似物——Virgaricins C和D 翻译改进
So-Ichiro Kimura 1, Yoshihiro Watanabe 1 2, Yudai Mikasa 3, Rei Miyano 1, Toshiyuki Tokiwa 2, Kenichi Nonaka 1 2, Takuji Nakashima 2, Yoshihiko Noguchi 1 2, Tomoyasu Hirose 1 2, Toshiaki Sunazuka 1 2, Rei Hokari 1 2, Aki Ishiyama 1 2, Masato Iwatsuki 4 5
作者单位 +展开
作者单位
1 Graduate School of Infection Control Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo, 108-8641, Japan.2 Ōmura Satoshi Memorial Institute, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo, 108-8641, Japan.3 School of Science, Kitasato University, 1-15-1, Kitazato, Minami-ku, Sagamihara, Kanagawa, 252-0373, Japan.4 Graduate School of Infection Control Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo, 108-8641, Japan. iwatuki@lisci.kitasato-u.ac.jp.5 Ōmura Satoshi Memorial Institute, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo, 108-8641, Japan. iwatuki@lisci.kitasato-u.ac.jp.
DOI: 10.1038/s41429-023-00699-8 PMID: 38302743
摘要 Ai翻译
Two new pramanicin analogs, named virgaricins C (1) and D (2), were discovered by physicochemical screening from a static cultured material of Apiospora sp. FKI-8058. Their structures were elucidated by MS and NMR analyses and chemical derivatization. Compounds 1 and 2 showed moderate antimalarial activity and cytotoxicity. © 2024. The Author(s), under exclusive licence... ...点击完成人机验证后继续浏览
Copyright © The Journal of antibiotics. 中文内容为AI机器翻译，仅供参考！
