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Frontiers in pharmacology. 2024 Jan 11:14:1268649. doi: 10.3389/fphar.2023.1268649 Q14.82025

Antifungal activity of the repurposed drug disulfiram against Cryptococcus neoformans

抗结核药物二硫异氰酸酯对新生隐球菌的抗真菌活性研究 翻译改进

Min Peng  1, Chen Zhang  1, Yuan-Yuan Duan  2, Hai-Bo Liu  1, Xin-Yuan Peng  1, Qian Wei  1  2, Qi-Ying Chen  1, Hong Sang  1, Qing-Tao Kong  1

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作者单位

  • 1 Department of Dermatology, Affiliated Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
  • 2 Affiliated Hospital for Skin Diseases, Chinese Academy of Medical Sciences, Nanjing, China.

    • DOI: 10.3389/fphar.2023.1268649 PMID: 38273827

    摘要 Ai翻译

    Fungal infections have become clinically challenging owing to the emergence of drug resistance in invasive fungi and the rapid increase in the number of novel pathogens. The development of drug resistance further restricts the use of antifungal agents. Therefore, there is an urgent need to identify alternative treatments for Cryptococcus neoformans (C. neoformans). Disulfiram (DSF) has a good human safety profile and promising applications as an antiviral,... ...点击完成人机验证后继续浏览
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    期刊名：Frontiers in pharmacology

    缩写：FRONT PHARMACOL

    ISSN：N/A

    e-ISSN：1663-9812

    IF/分区：4.8/Q1

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    Antifungal activity of the repurposed drug disulfiram against Cryptococcus neoformans