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The Journal of antibiotics. 2024 Apr;77(4):201-205. doi: 10.1038/s41429-023-00698-9 Q22.72025

Antibacterial p-terphenyl and α‑pyrone derivates isolated from the marine-derived actinomycete Nocardiopsis sp. HDN154086

来自海洋诺卡式菌株HDN154086的抗菌p-三联苯和α-吡喃衍生物 翻译改进

Luning Zhou  1, Yimin Chang  1, Shengkuan Yang  1, Xiaofei Huang  1, Jiaxiang Wang  1, Chengyu Jiang  2, Tianjiao Zhu  1  3, Dehai Li  4  5, Qian Che  6  7

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作者单位

  • 1 Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, PR China.
  • 2 Marine Biomedical Research Institute of Qingdao, Qingdao, 266237, PR China.
  • 3 Laboratory for Marine Drugs and Bioproducts of Qingdao Pilot National Laboratory for Marine Science and Technology, Qingdao, 266237, PR China.
  • 4 Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, PR China. dehaili@ouc.edu.cn.
  • 5 Laboratory for Marine Drugs and Bioproducts of Qingdao Pilot National Laboratory for Marine Science and Technology, Qingdao, 266237, PR China. dehaili@ouc.edu.cn.
  • 6 Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, PR China. cheqian064@ouc.edu.cn.
  • 7 Laboratory for Marine Drugs and Bioproducts of Qingdao Pilot National Laboratory for Marine Science and Technology, Qingdao, 266237, PR China. cheqian064@ouc.edu.cn.
  • DOI: 10.1038/s41429-023-00698-9 PMID: 38273126

    摘要 Ai翻译

    Assisted by OSMAC strategy, one new p-terphenyl and two new α‑pyrone derivates, namely nocarterphenyl I (1) and nocardiopyrone D-E (2-3), were obtained and characterized from the marine sediment-derived actinomycete Nocardiopsis sp. HDN154086. The structures of these compounds were determined on the basis of MS, NMR spectroscopic data and single-crystal X-ray diffraction. Compound 1 with a rare 2,2'-bithiazole structure among natural products showed prom... ...点击完成人机验证后继续浏览
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    期刊名:Journal of antibiotics

    缩写:J ANTIBIOT

    ISSN:0021-8820

    e-ISSN:1881-1469

    IF/分区:2.7/Q2

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    Antibacterial p-terphenyl and α‑pyrone derivates isolated from the marine-derived actinomycete Nocardiopsis sp. HDN154086