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Translational psychiatry. 2023 Nov 14;13(1):349. doi: 10.1038/s41398-023-02647-4 Q16.22025

The hippocampal FTO-BDNF-TrkB pathway is required for novel object recognition memory reconsolidation in mice

FTO-BDNF-TrkB通路是小鼠新物体识别记忆再巩固所必需的 hippocampal hippocampus应翻译为海马区 翻译改进

Rui Chang  1, Shanshan Zhu  1, Jionghong Peng  1, Zhenyi Lang  1, Xinyu Zhou  1, Hailin Liao  1, Ju Zou  1, Peng Zeng  2, Sijie Tan  3

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  • 1 Department of Histology and Embryology, School of Basic Medicine, Hengyang Medical School, University of South China, Hengyang, China.
  • 2 Department of Histology and Embryology, School of Basic Medicine, Hengyang Medical School, University of South China, Hengyang, China. zengp@hust.edu.cn.
  • 3 Department of Histology and Embryology, School of Basic Medicine, Hengyang Medical School, University of South China, Hengyang, China. sjtan@usc.edu.cn.

    • DOI: 10.1038/s41398-023-02647-4 PMID: 37963912

    摘要 Ai翻译

    Memory reconsolidation refers to the process by which the consolidated memory was restored after reactivation (RA). Memory trace becomes labile after reactivation and inhibition of memory reconsolidation may disrupt or update the original memory trace, which provided a new strategy for the treatment of several psychiatric diseases, such as drug addiction and post-traumatic stress disorder. Fat mass and obesity-associated gene (FTO) is a novel demethylase o... ...点击完成人机验证后继续浏览
    Copyright © Translational psychiatry. 中文内容为AI机器翻译，仅供参考！

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    期刊名：Translational psychiatry

    缩写：TRANSL PSYCHIAT

    ISSN：2158-3188

    e-ISSN：2158-3188

    IF/分区：6.2/Q1

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    The hippocampal FTO-BDNF-TrkB pathway is required for novel object recognition memory reconsolidation in mice