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Molecules (Basel, Switzerland). 2023 Feb 24;28(5):2148. doi: 10.3390/molecules28052148 Q24.62025

Berberine-Based Carbon Quantum Dots Improve Intestinal Barrier Injury and Alleviate Oxidative Stress in C57BL/6 Mice with 5-Fluorouracil-Induced Intestinal Mucositis by Enhancing Gut-Derived Short-Chain Fatty Acids Contents

基于小檗碱的碳量子点通过增强肠道短链脂肪酸改善C57BL/6小鼠5-氟尿嘧啶诱导的肠黏膜炎的肠道屏障损伤和氧化应激损伤 翻译改进

Liang Wu  1, Yue Xi  2, Man Yan  1, Chang Sun  1, Jiajun Tan  1, Jiayuan He  3, Haitao Li  4, Dongxu Wang  5

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作者单位

  • 1 Department of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang 212013, China.
  • 2 Medical Laboratory Department, Huai'an Second People's Hospital, Huai'an 223022, China.
  • 3 Health Testing Center, Zhenjiang Center for Disease Control and Prevention, Zhenjiang 212002, China.
  • 4 Energy Research Institute, Jiangsu University, Zhenjiang 212013, China.
  • 5 School of Grain Science and Technology, Jiangsu University of Science and Technology, Zhenjiang 212100, China.

    • DOI: 10.3390/molecules28052148 PMID: 36903391

    摘要 Ai翻译

    This study aims to evaluate the effect of berberine-based carbon quantum dots (Ber-CDs) on improving 5-fluorouracil (5-FU)-induced intestinal mucositis in C57BL/6 mice, and explored the mechanisms behind this effect. Thirty-two C57BL/6 mice were divided into four groups: normal control (NC), 5-FU-induced intestinal mucositis model (5-FU), 5-FU + Ber-CDs intervention (Ber-CDs), and 5-FU + native berberine intervention (Con-CDs). The Ber-CDs improved body we... ...点击完成人机验证后继续浏览
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    期刊名：Molecules

    缩写：MOLECULES

    ISSN：N/A

    e-ISSN：1420-3049

    IF/分区：4.6/Q2

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    Berberine-Based Carbon Quantum Dots Improve Intestinal Barrier Injury and Alleviate Oxidative Stress in C57BL/6 Mice with 5-Fluorouracil-Induced Intestinal Mucositis by Enhancing Gut-Derived Short-Chain Fatty Acids Contents