Russian chemical bulletin = Izvestiia Akademii nauk. Seriia khimicheskaia. 2023;72(1):233-238. doi: 10.1007/s11172-023-3728-y Q31.72024

Complexation ability of tetrasulfosubstituted cobalt(II) phthalocyanine toward ORF3a protein of SARS-CoV-2 virus

四磺化钴(II)酞菁与SARS-CoV-2病毒ORF3a蛋白的配位能力研究翻译改进

O I Koifman^{1 2}, V E Maizlish², M O Koifman^{1 2}, N Sh Lebedeva¹, E S Yurina¹, Yu A Gubarev¹, E L Gur'ev³

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作者单位

¹ G. A. Krestov Institute of Solution Chemistry, Russian Academy of Sciences, 1 ul. Akademicheskaya, 153045 Ivanovo, Russian Federation.

² Ivanovo State University of Chemistry and Technology, 7 Sheremetevskii prosp., 153000 Ivanovo, Russian Federation.

³ Lobachesky State University of Nizhny Novgorod, 4 Ashkhabadskaya ul., 603105 Nizhny Novgorod, Russian Federation.

DOI: 10.1007/s11172-023-3728-y PMID: 36817559

摘要 Ai翻译

Complex formation processes of tetrasulfosubstituted cobalt(II) phthalocyanine with ORF3a accessory protein of SARS-CoV-2 coronavirus were studied. The interaction of ORF3a protein with SARS-CoV-2 virus with tetrasulfosubstituted cobalt(II) phthalocyanine affords a stable complex in which metallophthalocyanine exists in the monomeric form. The complex formation induces slight changes in the secondary structure of the protein by increasing the fraction of disordered fragments of the polypeptide chain. The photoirradiation of the complex of ORF3a protein of SARS-CoV-2 virus with tetrasulfosubstituted cobalt(II) phthalocyanine leads to the photooxidation of amino acid residues of the protein.

Keywords: complex formation; photooxidation; phthalocyanine; protein; virus SARS-CoV-2.

Keywords：orf3a protein; sars-cov-2病毒; complexation ability

关键词：ORF3a蛋白; SARS-CoV-2病毒; 配位能力

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期刊名：Russian chemical bulletin

缩写：RUSS CHEM B+

ISSN：1066-5285

e-ISSN：1573-9171

IF/分区：1.7/Q3

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Complexation ability of tetrasulfosubstituted cobalt(II) phthalocyanine toward ORF3a protein of SARS-CoV-2 virus

四磺化钴(II)酞菁与SARS-CoV-2病毒ORF3a蛋白的配位能力研究翻译改进

[In vitro activity of human recombinant alpha-2b interferon against SARS-CoV-2 virus]

人干扰素α-2b对SARS-CoV-2的体外活性研究

Profile of SARS-CoV-2

新型冠状病毒(SARS-CoV-2)的特性分析

Chitosan derivatives: A suggestive evaluation for novel inhibitor discovery against wild type and variants of SARS-CoV-2 virus

壳聚糖衍生物：针对SARS-CoV-2病毒野生株及变异株的新型抑制剂筛选评估研究报告

A triple-target reverse transcription loop-mediated isothermal amplification (RT-LAMP) for rapid and accurate detection of SARS-CoV-2 virus

一种针对SARS-CoV-2病毒的三靶点反转录环介导等温扩增(RT-LAMP)快速精准检测方法

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COPD患者是否能抵御SARS-CoV-2病毒？

SARS-CoV-2 docet

新型冠状病毒文献计量学分析

Detecting SARS-CoV-2 Virus by Reverse Transcription-Loop-mediated Isothermal Amplification

逆转录环介导等温扩增技术检测SARS-CoV-2病毒

Confirmatory Virucidal Activity of Ionised Active Water S-100® on the SARS-CoV-2 Virus

离子态活性水S-100®对SARS-CoV-2病毒的确认灭活作用

Complexation ability of tetrasulfosubstituted cobalt(II) phthalocyanine toward ORF3a protein of SARS-CoV-2 virus

四磺化钴(II)酞菁与SARS-CoV-2病毒ORF3a蛋白的配位能力研究 翻译改进

[In vitro activity of human recombinant alpha-2b interferon against SARS-CoV-2 virus]

人干扰素α-2b对SARS-CoV-2的体外活性研究

Profile of SARS-CoV-2

新型冠状病毒(SARS-CoV-2)的特性分析

Chitosan derivatives: A suggestive evaluation for novel inhibitor discovery against wild type and variants of SARS-CoV-2 virus

壳聚糖衍生物：针对SARS-CoV-2病毒野生株及变异株的新型抑制剂筛选评估研究报告

A triple-target reverse transcription loop-mediated isothermal amplification (RT-LAMP) for rapid and accurate detection of SARS-CoV-2 virus

一种针对SARS-CoV-2病毒的三靶点反转录环介导等温扩增(RT-LAMP)快速精准检测方法

Is a COPD patient protected against SARS-CoV-2 virus?

COPD患者是否能抵御SARS-CoV-2病毒？

SARS-CoV-2 docet

新型冠状病毒文献计量学分析

Detecting SARS-CoV-2 Virus by Reverse Transcription-Loop-mediated Isothermal Amplification

逆转录环介导等温扩增技术检测SARS-CoV-2病毒

Confirmatory Virucidal Activity of Ionised Active Water S-100® on the SARS-CoV-2 Virus

离子态活性水S-100®对SARS-CoV-2病毒的确认灭活作用

四磺化钴(II)酞菁与SARS-CoV-2病毒ORF3a蛋白的配位能力研究翻译改进