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Acta mathematica scientia = Shu xue wu li xue bao. 2022;42(5):2087-2112. doi: 10.1007/s10473-022-0521-1 Q21.22024

Probing a Stochastic Epidemic Hepatitis C Virus Model with a Chronically Infected Treated Population

具有慢性感染治疗人群的随机流行性肝炎C病毒模型探究 翻译改进

S P Rajasekar  1  2, M Pitchaimani  1, Quanxin Zhu  3

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作者单位

  • 1 Ramanujan Institute for Advanced Study in Mathematics, University of Madras, Chennai, Tamil Nadu, 600 005 India.
  • 2 Department of Mathematics, Government Arts College for Women, Nilakottai, Tamil Nadu, 624 202 India.
  • 3 CHP-LCOCS, School of Mathematics and Statistics, Hunan Normal University, Changsha, 410081 China.
  • DOI: 10.1007/s10473-022-0521-1 PMID: 35911571

    摘要 Ai翻译

    The hepatitis C virus is hitherto a tremendous threat to human beings, but many researchers have analyzed mathematical models for hepatitis C virus transmission dynamics only in the deterministic case. Stochasticity plays an immense role in pathology and epidemiology. Hence, the main theme of this article is to investigate a stochastic epidemic hepatitis C virus model with five states of epidemiological classification: susceptible, acutely infected, chronically infected, recovered or removed and chronically infected, and treated. The stochastic hepatitis C virus model in epidemiology is established based on the environmental influence on individuals, is manifested by stochastic perturbations, and is proportional to each state. We assert that the stochastic HCV model has a unique global positive solution and attains sufficient conditions for the extinction of the hepatotropic RNA virus. Furthermore, by constructing a suitable Lyapunov function, we obtain sufficient conditions for the existence of an ergodic stationary distribution of the solutions to the stochastic HCV model. Moreover, this article confirms that using numerical simulations, the six parameters of the stochastic HCV model can have a high impact over the disease transmission dynamics, specifically the disease transmission rate, the rate of chronically infected population, the rate of progression to chronic infection, the treatment failure rate of chronically infected population, the recovery rate from chronic infection and the treatment rate of the chronically infected population. Eventually, numerical simulations validate the effectiveness of our theoretical conclusions.

    Keywords: acute and chronically infected; chronically infected treated; extinction; hepatitis C virus; stationary distribution.

    Keywords:stochastic epidemic model; hepatitis c virus; treated population

    Copyright © Acta mathematica scientia = Shu xue wu li xue bao. 中文内容为AI机器翻译,仅供参考!

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    期刊名:Acta mathematica scientia

    缩写:ACTA MATH SCI

    ISSN:0252-9602

    e-ISSN:1572-9087

    IF/分区:1.2/Q2

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    Probing a Stochastic Epidemic Hepatitis C Virus Model with a Chronically Infected Treated Population