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Chemical communications (Cambridge, England). 2022 Aug 16;58(66):9210-9213. doi: 10.1039/d2cc01515c Q24.22025

A unique water soluble probe for measuring the cardiac marker homocysteine and its clinical validation

一种测量心脏标志物同型半胱氨酸的独特的水溶性探针及其临床验证 翻译改进

Snehasish Debnath  1  2, Ratish R Nair  1  2, Riya Ghosh  1  2, Gaddam Kiranmai  3, Narsini Radhakishan  4, Narayana Nagesh  3, Pabitra B Chatterjee  1  2

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作者单位

  • 1 Analytical & Environmental Science Division and Centralized Instrument Facility, CSIR-CSMCRI, G. B. Marg, Bhavnagar, Gujarat, India. pbchatterjee@csmcri.res.in.
  • 2 Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
  • 3 Medical Biotechnology Complex, CSIR-CCMB, ANNEXE II, Hyderabad, Telangana, India. nagesh@ccmb.res.in.
  • 4 Department of Biochemistry, Nizam's Institute of Medical Sciences, Punjagutta, Hyderabad, Telangana, India.

    • DOI: 10.1039/d2cc01515c PMID: 35895029

    摘要 Ai翻译

    A series of copper(II) compounds 1-4 were synthesized and developed as fluorogenic probes to measure the cardiac marker homocysteine (Hcy) without any interference from other bioanalytes prevalent in human blood plasma including, cysteine and glutathione. UV-vis and EPR studies have provided confirmatory evidence for reduction-induced-emission-enhancement of the probe, which is responsible for the observed "off-to-on" behaviour towards Hcy. Water solubilit... ...点击完成人机验证后继续浏览
    Copyright © Chemical communications (Cambridge, England). 中文内容为AI机器翻译，仅供参考！

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    期刊名：Chemical communications

    缩写：CHEM COMMUN

    ISSN：1359-7345

    e-ISSN：1364-548X

    IF/分区：4.2/Q2

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    A unique water soluble probe for measuring the cardiac marker homocysteine and its clinical validation