Virulence. 2021 Dec;12(1):377-388. doi: 10.1080/21505594.2020.1867468 Q15.42025

Convergence of carbapenem resistance and hypervirulence in a highly-transmissible ST11 clone of K. pneumoniae: An epidemiological, genomic and functional study

碳青霉烯耐药性和高毒力在高传播性克雷伯氏肺炎菌ST11克隆中汇聚的流行病学、基因组和功能研究翻译改进

Ping Li¹, Qiqiang Liang¹, Wugao Liu², Beiwen Zheng³, Lizhang Liu¹, Wei Wang², Zhijiang Xu⁴, Man Huang¹, Youjun Feng^{1 5 6}

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¹ Department of Pathogen Biology & Microbiology and Department of General Intensive Care Unit of the Second Affiliated Hospital, Zhejiang University School of Medicine , Hangzhou, Zhejiang China.

² Clinical Laboratory of Lishui People's Hospital , Lishui, China.

³ The First Affiliated Hospital, Zhejiang University School of Medicine , Hangzhou, China.

⁴ Clinical Laboratory, the Second Affiliated Hospital, Zhejiang University School of Medicine , Hangzhou, China.

⁵ Non-coding RNA and Drug Discovery Key Laboratory of Sichuan Province, Chengdu Medical College , Chengdu, China.

⁶ College of Animal Sciences, Zhejiang University , Hangzhou, China.

DOI: 10.1080/21505594.2020.1867468 PMID: 33356821

摘要 Ai翻译

Co-occurrence of hypervirulence and KPC-2 carbapenem resistant phenotypes in a highly-transmissible ST11 clone ofKlebsiella pneumoniae has elicited deep concerns from public health stand point. To address this puzzle, we conducted a large-scale epidemiological, clinical and genomic study of K. pneumonia ST11 clones with both hypervirulence and carbapenem resistance in two tertiary hospitals in Zhejiang province. Most of the patients (15/23) were diagnosed ... ...点击完成人机验证后继续浏览

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期刊名：Virulence

缩写：VIRULENCE

ISSN：2150-5594

e-ISSN：2150-5608

IF/分区：5.4/Q1

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Convergence of carbapenem resistance and hypervirulence in a highly-transmissible ST11 clone of K. pneumoniae: An epidemiological, genomic and functional study

碳青霉烯耐药性和高毒力在高传播性克雷伯氏肺炎菌ST11克隆中汇聚的流行病学、基因组和功能研究翻译改进

Convergence of carbapenem resistance and hypervirulence leads to high mortality in patients with postoperative Klebsiella pneumoniae meningitis

碳青霉烯类耐药与高毒力克雷伯菌汇合导致术后肺炎克雷伯菌脑膜炎患者病死率极高

Convergence of carbapenem-resistance and hypervirulence in Klebsiella pneumoniae

碳青霉烯耐药性与条件致病菌肺炎克雷伯菌毒力的汇聚趋势

Hypervirulence Markers Among Non-ST11 Strains of Carbapenem- and Multidrug-Resistant Klebsiella pneumoniae Isolated From Patients With Bloodstream Infections

从感染鲍曼不动杆菌血流感染患者中鉴定出碳青霉烯耐药及多重耐药非ST258型序列型菌株的高毒力标志物

A global perspective on the convergence of hypervirulence and carbapenem resistance in Klebsiella pneumoniae

肺炎克雷伯菌泛耐碳氢酶烯和高毒力融合的全球性观点

Convergent Klebsiella pneumoniae strains belonging to a sequence type 307 outbreak clone combine cefiderocol and carbapenem resistance with hypervirulence

具序列型307爆发克隆特征的新德里金属蛋白酶碳青霉烯酶产生肺炎克雷伯菌的耐药性及高毒力特征分析

Hypervirulence and carbapenem resistance: two distinct evolutionary directions that led high-risk Klebsiella pneumoniae clones to epidemic success

高毒力和碳青霉烯耐药性：两种不同的进化方向使高风险肺炎克雷伯菌克隆成功流行

The novel outer membrane protein from OprD/Occ family is associated with hypervirulence of carbapenem resistant Acinetobacter baumannii ST2/KL22

碳青霉烯耐药的ST2／KL22型鲍曼不动杆菌新型外膜蛋白与高毒力相关

Conjugation of a Hybrid Plasmid Encoding Hypervirulence and Carbapenem Resistance in Klebsiella pneumoniae of Sequence Type 592

肺炎克雷伯菌序列型592携带超广谱碳青霉烯耐药质粒的接合转移研究

Convergence of carbapenem resistance and hypervirulence in a highly-transmissible ST11 clone of K. pneumoniae: An epidemiological, genomic and functional study

碳青霉烯耐药性和高毒力在高传播性克雷伯氏肺炎菌ST11克隆中汇聚的流行病学、基因组和功能研究 翻译改进

Convergence of carbapenem resistance and hypervirulence leads to high mortality in patients with postoperative Klebsiella pneumoniae meningitis

碳青霉烯类耐药与高毒力克雷伯菌汇合导致术后肺炎克雷伯菌脑膜炎患者病死率极高

Convergence of carbapenem-resistance and hypervirulence in Klebsiella pneumoniae

碳青霉烯耐药性与条件致病菌肺炎克雷伯菌毒力的汇聚趋势

Hypervirulence Markers Among Non-ST11 Strains of Carbapenem- and Multidrug-Resistant Klebsiella pneumoniae Isolated From Patients With Bloodstream Infections

从感染鲍曼不动杆菌血流感染患者中鉴定出碳青霉烯耐药及多重耐药非ST258型序列型菌株的高毒力标志物

A global perspective on the convergence of hypervirulence and carbapenem resistance in Klebsiella pneumoniae

肺炎克雷伯菌泛耐碳氢酶烯和高毒力融合的全球性观点

Convergent Klebsiella pneumoniae strains belonging to a sequence type 307 outbreak clone combine cefiderocol and carbapenem resistance with hypervirulence

具序列型307爆发克隆特征的新德里金属蛋白酶碳青霉烯酶产生肺炎克雷伯菌的耐药性及高毒力特征分析

Hypervirulence and carbapenem resistance: two distinct evolutionary directions that led high-risk Klebsiella pneumoniae clones to epidemic success

高毒力和碳青霉烯耐药性：两种不同的进化方向使高风险肺炎克雷伯菌克隆成功流行

The novel outer membrane protein from OprD/Occ family is associated with hypervirulence of carbapenem resistant Acinetobacter baumannii ST2/KL22

碳青霉烯耐药的ST2／KL22型鲍曼不动杆菌新型外膜蛋白与高毒力相关

Conjugation of a Hybrid Plasmid Encoding Hypervirulence and Carbapenem Resistance in Klebsiella pneumoniae of Sequence Type 592

肺炎克雷伯菌序列型592携带超广谱碳青霉烯耐药质粒的接合转移研究

碳青霉烯耐药性和高毒力在高传播性克雷伯氏肺炎菌ST11克隆中汇聚的流行病学、基因组和功能研究翻译改进