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Angewandte Chemie (International ed. in English). 2018 Sep 24;57(39):12799-12803. doi: 10.1002/anie.201807775 Q116.92025

Enantioselective Construction of Tertiary Boronic Esters by Conjunctive Cross-Coupling

串联交叉偶联法构建 tertiary 烷基硼酸酯类映异构体 翻译改进

Jesse A Myhill  1, Liang Zhang  1, Gabriel J Lovinger  1, James P Morken  1

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作者单位

  • 1 Department of Chemistry, Boston College, 2609 Beacon Street, Chestnut Hill, MA, 02467, USA.
  • DOI: 10.1002/anie.201807775 PMID: 30091829

    摘要 Ai翻译

    Catalytic enantioselective conjunctive cross-coupling has been developed to construct tertiary alkylboronic esters. These reactions occur with good yield and enantioselectivity for a range of substrates. Mechanistic experiments reveal aspects of the catalytic cycle that allow hindered substrates to react without significant complicating side reactions.

    Keywords: asymmetric catalysis; boron; cross coupling; quaternary centers.

    Keywords:enantioselective construction; tertiary boronic esters; conjunctive cross-coupling

    Copyright © Angewandte Chemie (International ed. in English). 中文内容为AI机器翻译,仅供参考!

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    期刊名:Angewandte chemie-international edition

    缩写:ANGEW CHEM INT EDIT

    ISSN:N/A

    e-ISSN:1521-3773

    IF/分区:16.9/Q1

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    Enantioselective Construction of Tertiary Boronic Esters by Conjunctive Cross-Coupling