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Review Blood. 2018 Apr 26;131(17):1903-1909. doi: 10.1182/blood-2017-04-569111 Q123.12025

Coagulation factor XII in thrombosis and inflammation

凝血因子XII在血栓形成和炎症中的作用 翻译改进

Coen Maas  1, Thomas Renné  2

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作者单位

  • 1 Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht, The Netherlands; and.
  • 2 Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • DOI: 10.1182/blood-2017-04-569111 PMID: 29483100

    摘要 Ai翻译

    Combinations of proinflammatory and procoagulant reactions are the unifying principle for a variety of disorders affecting the cardiovascular system. The factor XII-driven contact system starts coagulation and inflammatory mechanisms via the intrinsic pathway of coagulation and the bradykinin-producing kallikrein-kinin system, respectively. The biochemistry of the contact system in vitro is well understood; however, its in vivo functions are just beginning... ...点击完成人机验证后继续浏览
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    期刊名:Blood

    缩写:BLOOD

    ISSN:0006-4971

    e-ISSN:1528-0020

    IF/分区:23.1/Q1

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    Coagulation factor XII in thrombosis and inflammation