A novel and efficient copper-catalyzed radical cross-coupling of 1,3-dicarbonyl compounds with terminal alkenes for the synthesis of tetracarbonyl compounds with a quaternary carbon atom has been developed. Mechanistically, this transformation involves the construction of two C-C bonds and two C[double bond, length as m-dash]O bonds in a one-pot process. The reaction tolerates a wide range of functional groups and proceeds under mild conditions.
Chemical communications (Cambridge, England). 2016 May 4;52(36):6127-30. doi: 10.1039/c6cc01942k Q24.32024
Copper-catalyzed radical coupling of 1,3-dicarbonyl compounds with terminal alkenes for the synthesis of tetracarbonyl compounds
铜催化1,3-二羰基化合物与末端烯烃的自由基偶联反应合成四羰基化合物 翻译改进
作者单位 +展开
作者单位
DOI: 10.1039/c6cc01942k PMID: 27071461
摘要 Ai翻译
相关内容
-
Copper-Catalyzed Radical/Radical C(sp 3)-H/P-H Cross-Coupling: α-Phosphorylation of Aryl Ketone O-Acetyloximes
铜催化的自由基/自由基C(sp 3)―H/P―H交叉偶联反应：芳酮O-乙酰氧亚胺的α-磷酸化反应
Angewandte Chemie (International ed. in English). 2015 May 26;54(22):6604-7.
-
A copper-catalyzed insertion of sulfur dioxide via radical coupling
经自由基偶联的二氧化硫的铜催化插入反应
Chemical communications (Cambridge, England). 2020 Mar 12;56(21):3225-3228.
-
Copper-Catalyzed Regioselective Aminothiolation of Aromatic and Aliphatic Alkenes with N-Fluorobenzenesulfonimide and Thiols through Three-Component Radical Coupling
铜催化N-氟代苯磺酰亚胺/硫醇与芳基和烷基烯烃的区域选择性氨基硫化反应三组分自由基偶联反应
The Journal of organic chemistry. 2019 Dec 6;84(23):15373-15379.
-
Copper-Catalyzed Enantioconvergent Radical C(sp3)-N Cross-Coupling to Access Chiral α-Amino-β-lactams
铜催化对映汇聚型自由基C（sp3）-N交叉偶联反应构建手性α-氨基酸-β-内酰胺化合物
Precision chemistry. 2023 Oct 10;1(10):576-582.
-
Copper-catalyzed selective radical-radical cross-coupling for C-S bond formation: an access to α-alkylthionitriles
铜催化自由基-自由基交叉偶联选择性构建硫碳键：α-烷基硫氰化合物的合成新策略
Chemical communications (Cambridge, England). 2018 May 29;54(44):5574-5577.
-
Alkali-Metal Aminotroponiminates: Selectivities and Equilibria in Reversible Radical Coupling of Delocalized π-Electron Systems
碱金属氨氨基莫加内酯：离域π电子系统的可逆自由基偶联的选择性和平衡性
Chemistry (Weinheim an der Bergstrasse, Germany). 2019 Sep 12;25(51):11883-11891.
-
Copper-catalyzed α-amination of aliphatic aldehydes
脂肪族醛的铜催化α氨基化反应
Chemical communications (Cambridge, England). 2011 May 21;47(19):5458-60.
-
Radical Nature of Cu-Catalyzed Controlled Radical Polymerizations (Atom Transfer Radical Polymerization)
铜催化可控自由基聚合的革命性进展（原子转移自由基聚合）
Macromolecules. 1998 Jul 28;31(15):4710-7.
