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Review Expert opinion on drug delivery. 2017 Feb;14(2):245-255. doi: 10.1080/17425247.2016.1213237 Q15.42025

Cell-penetrating peptides with intracellular organelle targeting

具有细胞器定位的细胞穿膜肽 翻译改进

Carmine Pasquale Cerrato  1, Kadri Künnapuu  2, Ülo Langel  1  2

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作者单位

  • 1 a Department of Neurochemistry , Stockholm University , Stockholm , Sweden.
  • 2 b Laboratory of Molecular Biotechnology, Institute of Technology , University of Tartu , Tartu , Estonia.
  • DOI: 10.1080/17425247.2016.1213237 PMID: 27426871

    摘要 Ai翻译

    One of the major limiting steps in order to have an effective drug is the passage through one or more cell membranes to reach its site of action. To reach the action-site, the specific macromolecules are required to be delivered specifically to the cell compartment/organelle in their (pre)active form. Areas covered: In this review, we will discuss cell-penetrating peptides (CPPs) developed in the last decade to transport small RNA/DNA, plasmids, antibodies... ...点击完成人机验证后继续浏览
    Copyright © Expert opinion on drug delivery. 中文内容为AI机器翻译,仅供参考!

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    期刊名:Expert opinion on drug delivery

    缩写:EXPERT OPIN DRUG DEL

    ISSN:1742-5247

    e-ISSN:1744-7593

    IF/分区:5.4/Q1

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    Cell-penetrating peptides with intracellular organelle targeting