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Review Journal of gastroenterology. 2017 Mar;52(3):265-275. doi: 10.1007/s00535-016-1272-3 Q15.52025

Molecular pathological epidemiology: new developing frontiers of big data science to study etiologies and pathogenesis

分子病理学流行病学：大数据科学研究病因和发病机制的新前沿领域 翻译改进

Tsuyoshi Hamada  1, NaNa Keum  2, Reiko Nishihara  3  4  5  6, Shuji Ogino  7  8  9  10

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作者单位

  • 1 Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, 450 Brookline Ave., Room SM1036, Boston, MA, 02215, USA.
  • 2 Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
  • 3 Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, 450 Brookline Ave., Room SM1036, Boston, MA, 02215, USA. rnishiha@hsph.harvard.edu.
  • 4 Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA. rnishiha@hsph.harvard.edu.
  • 5 Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA. rnishiha@hsph.harvard.edu.
  • 6 Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA. rnishiha@hsph.harvard.edu.
  • 7 Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, 450 Brookline Ave., Room SM1036, Boston, MA, 02215, USA. shuji_ogino@dfci.harvard.edu.
  • 8 Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA. shuji_ogino@dfci.harvard.edu.
  • 9 Division of MPE Molecular Pathological Epidemiology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, 450 Brookline Ave., Room SM1036, Boston, MA, 02215, USA. shuji_ogino@dfci.harvard.edu.
  • 10 Department of Oncologic Pathology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA. shuji_ogino@dfci.harvard.edu.

    • DOI: 10.1007/s00535-016-1272-3 PMID: 27738762

    摘要 Ai翻译

    Molecular pathological epidemiology (MPE) is an integrative field that utilizes molecular pathology to incorporate interpersonal heterogeneity of a disease process into epidemiology. In each individual, the development and progression of a disease are determined by a unique combination of exogenous and endogenous factors, resulting in different molecular and pathological subtypes of the disease. Based on "the unique disease principle," the primary aim of M... ...点击完成人机验证后继续浏览
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    期刊名：Journal of gastroenterology

    缩写：J GASTROENTEROL

    ISSN：0944-1174

    e-ISSN：1435-5922

    IF/分区：5.5/Q1

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    Molecular pathological epidemiology: new developing frontiers of big data science to study etiologies and pathogenesis