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American journal of cancer research. 2011;1(3):301-327. Q22.92025

The ups and downs of DNA repair biomarkers for PARP inhibitor therapies

DNA修复生物标志物在PARP抑制剂治疗中的起伏 翻译改进

Xiaozhe Wang  1, David T Weaver

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  • 1 On-Q-ity, Inc. 610 Lincoln St. Waltham, Massachusetts, 02451, USA.
  • PMID: 21968427

    摘要 Ai翻译

    PARP inhibitors are emerging as a valuable new drug class in the treatment of cancer. Recent discoveries make a compelling case for the complexity of DNA repair biomarker evaluation and underscore the need to examine at multiple biomarkers in a relational manner. This review updates the current trends in DNA repair biomarker strategies in use for the PARP inhibitors and describes the impact of many DNA repair biomarkers on PARP inhibitor benefit in the can... ...点击完成人机验证后继续浏览
    Copyright © American journal of cancer research. 中文内容为AI机器翻译,仅供参考!

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    期刊名:American journal of cancer research

    缩写:AM J CANCER RES

    ISSN:2156-6976

    e-ISSN:2156-6976

    IF/分区:2.9/Q2

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    The ups and downs of DNA repair biomarkers for PARP inhibitor therapies