The application of phosphorescent heavy-metal complexes with d(6), d(8) and d(10) electron configurations for bioimaging is a new and promising research field and has been attracting increasing interest. In this critical review, we systematically evaluate the advantages of phosphorescent heavy-metal complexes as bioimaging probes, including their photophysical properties, cytotoxicity and cellular uptake mechanisms. The progress of research into the use of phosphorescent heavy-metal complexes for staining different compartments of cells, monitoring intracellular functional species, providing targeted bioimaging, two-photon bioimaging, small-animal bioimaging, multimodal bioimaging and time-resolved bioimaging is summarized. In addition, several possible future directions in this field are also discussed (133 references).
Review Chemical Society reviews. 2011 May;40(5):2508-24. doi: 10.1039/c0cs00114g Q140.42024
Phosphorescent heavy-metal complexes for bioimaging
用于生物成像的长余辉重金属配合物 翻译改进
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DOI: 10.1039/c0cs00114g PMID: 21253643
摘要 Ai翻译
Keywords：bioimaging
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