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Journal of immunology (Baltimore, Md. : 1950). 2010 Jun 1;184(11):6242-8. doi: 10.4049/jimmunol.1000507 Q23.42025

Switch region identity plays an important role in Ig class switch recombination

切换区身份在Ig类别转换重组中起重要作用 翻译改进

Palash Bhattacharya  1, Robert Wuerffel, Amy L Kenter

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  • 1 Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, IL 60612-7344, USA.
  • DOI: 10.4049/jimmunol.1000507 PMID: 20427773

    摘要 Ai翻译

    Ig class switch recombination (CSR) is regulated through long-range intrachromosomal interactions between germline transcript promoters and enhancers to initiate transcription and create chromatin accessible to activation-induced deaminase attack. CSR occurs between switch (S) regions that flank Cmu and downstream C(H) regions and functions via an intrachromosomal deletional event between the donor Smicro region and a downstream S region. It is unclear to ... ...点击完成人机验证后继续浏览
    Copyright © Journal of immunology (Baltimore, Md. : 1950). 中文内容为AI机器翻译,仅供参考!

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    期刊名:Journal of immunology

    缩写:J IMMUNOL

    ISSN:0022-1767

    e-ISSN:1550-6606

    IF/分区:3.4/Q2

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    Switch region identity plays an important role in Ig class switch recombination