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Autophagy. 2010 Feb;6(2):290-1. doi: 10.4161/auto.6.2.11127 Q114.32025

Autophagy takes an alternative pathway

自噬走另条路 翻译改进

Shigeomi Shimizu  1, Satoko Arakawa, Yuya Nishida

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作者单位

  • 1 Department of Pathological Cell Biology, Medical Research Institute, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan. shimizu.pcb@mri.tmd.ac.jp
  • DOI: 10.4161/auto.6.2.11127 PMID: 20104021

    摘要 Ai翻译

    ATG5 and ATG7 are considered as essential molecules for induction of macroautophagy. However, we found that cells lacking ATG5 or ATG7 can still form autophagosomes/autolysosomes and perform autophagy-mediated protein degradation when subjected to certain stresses. Although lipidation of LC3 is accepted to be a good indicator of macroautophagy, it did not occur during the ATG5/ATG7-independent alternative macroautophagy. Unlike conventional macroautophagy,... ...点击完成人机验证后继续浏览
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    期刊名:Autophagy

    缩写:AUTOPHAGY

    ISSN:1554-8627

    e-ISSN:1554-8635

    IF/分区:14.3/Q1

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