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The Journal of organic chemistry. 2009 Dec 18;74(24):9562-5. doi: 10.1021/jo902106r Q13.62025

Proline-beta(3)-amino-ester dipeptides as efficient catalysts for enantioselective direct aldol reaction in aqueous medium

脯氨酸衍生物催化水相直接动力学拆分反应研究进展 翻译改进

Mauro De Nisco  1, Silvana Pedatella, Hidayat Ullah, Javid H Zaidi, Daniele Naviglio, Ozgür Ozdamar, Romualdo Caputo

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作者单位

  • 1 Dipartimento di Chimica Organica e Biochimica, Università di Napoli Federico II, Via Cintia, 4 Napoli 80126, Italy. denisco@unina.it
  • DOI: 10.1021/jo902106r PMID: 19938836

    摘要 Ai翻译

    Dipeptides obtained from l-proline and beta(3)-l-amino acids are reported to catalyze enantioselective direct aldol reaction in aqueous medium, leading to significant anti:syn diastereomeric ratios and enantiomeric excesses. The simple introduction of a polar substituent at the C-2 position of the beta(3)-l-amino acid was also found to enhance appreciably both diastereo- and enantioselectivity of the catalyst. ... ...点击完成人机验证后继续浏览
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    期刊名:Journal of organic chemistry

    缩写:J ORG CHEM

    ISSN:0022-3263

    e-ISSN:1520-6904

    IF/分区:3.6/Q1

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    Proline-beta(3)-amino-ester dipeptides as efficient catalysts for enantioselective direct aldol reaction in aqueous medium