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Free radical biology & medicine. 2009 Nov 15;47(10):1414-21. doi: 10.1016/j.freeradbiomed.2009.08.008 Q18.22025

Trypanosoma cruzi infection disturbs mitochondrial membrane potential and ROS production rate in cardiomyocytes

恰加斯病原虫感染扰乱心肌细胞的线粒体膜电位和活性氧生成速率 翻译改进

Shivali Gupta  1, Vandanajay Bhatia, Jian-jun Wen, Yewen Wu, Ming-He Huang, Nisha Jain Garg

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  • 1 Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA.
  • DOI: 10.1016/j.freeradbiomed.2009.08.008 PMID: 19686837

    摘要 Ai翻译

    In this study, we investigated the role of Trypanosoma cruzi invasion and inflammatory processes in reactive oxygen species (ROS) production in a mouse atrial cardiomyocyte line (HL-1) and primary adult rat ventricular cardiomyocytes. Cardiomyocytes were incubated with T. cruzi (Tc) trypomastigotes, Tc lysate (TcTL), or Tc secreted proteins (TcSP) for 0-72 h, and ROS were measured by amplex red assay. Cardiomyocytes infected by T. cruzi (but not those incu... ...点击完成人机验证后继续浏览
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    期刊名:Free radical biology and medicine

    缩写:FREE RADICAL BIO MED

    ISSN:0891-5849

    e-ISSN:1873-4596

    IF/分区:8.2/Q1

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    Trypanosoma cruzi infection disturbs mitochondrial membrane potential and ROS production rate in cardiomyocytes