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Behavioural brain research. 2008 Dec 12;194(2):129-37. doi: 10.1016/j.bbr.2008.06.006 Q22.32025

Cellular prion protein modulates defensive attention and innate fear-induced behaviour evoked in transgenic mice submitted to an agonistic encounter with the tropical coral snake Oxyrhopus guibei

小细胞毒扁尾海蛇诱发转基因小鼠攻击性遭遇中的防御注意力和先天恐惧行为受到细胞内原核蛋白的调节 翻译改进

Bruno Lobão-Soares  1, Roger Walz, Rui Daniel Schröder Prediger, Renato Leonardo Freitas, Fabrício Calvo, Marino Muxfeldt Bianchin, João Pereira Leite, Michele Christine Landemberger, Norberto Cysne Coimbra

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作者单位

  • 1 Laboratory of Neuroanatomy & Neuropsychobiology, Department of Pharmacology, School of Medicine of Ribeirão Preto of the University of São Paulo (USP), Av. dos Bandeirantes 3900, Ribeirão Preto, São Paulo (SP), 14049-900, Brazil.
  • DOI: 10.1016/j.bbr.2008.06.006 PMID: 18590772

    摘要 Ai翻译

    The cellular prion protein (PrP(C)) is a neuronal anchored glycoprotein that has been associated with distinct functions in the CNS, such as cellular adhesion and differentiation, synaptic plasticity and cognition. Here we investigated the putative involvement of the PrP(C) in the innate fear-induced behavioural reactions in wild-type (WT), PrP(C) knockout (Prnp(0/0)) and the PrP(C) overexpressing Tg-20 mice evoked in a prey versus predator paradigm. The b... ...点击完成人机验证后继续浏览
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    期刊名:Behavioural brain research

    缩写:BEHAV BRAIN RES

    ISSN:0166-4328

    e-ISSN:1872-7549

    IF/分区:2.3/Q2

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    Cellular prion protein modulates defensive attention and innate fear-induced behaviour evoked in transgenic mice submitted to an agonistic encounter with the tropical coral snake Oxyrhopus guibei