首页 正文

FEBS letters. 2001 Jun 22;499(3):215-9. doi: 10.1016/s0014-5793(01)02557-1 Q23.02025

Requirements of basic amino acid residues within the lectin-like domain of LOX-1 for the binding of oxidized low-density lipoprotein

氧化低密度脂蛋白与LOX-1类似凝集素结构域中基本氨基酸残基的要求 翻译改进

M Chen  1, K Inoue, S Narumiya, T Masaki, T Sawamura

作者单位 +展开

作者单位

  • 1 National Cardiovascular Center Research Institute, Suita, Osaka, Japan.
  • DOI: 10.1016/s0014-5793(01)02557-1 PMID: 11423119

    摘要 Ai翻译

    Lectin-like OxLDL receptor-1 (LOX-1) was identified as the major receptor for oxidized low-density lipoprotein (OxLDL) in aortic endothelial cells. LOX-1 is a type II membrane protein that structurally belongs to the C-type lectin family. Here, we found that the lectin-like domain of LOX-1 is essential for ligand binding, but the neck domain is not. In particular, the large loop between the third and fourth cysteine of the lectin-like domain plays a critic... ...点击完成人机验证后继续浏览
    Copyright © FEBS letters. 中文内容为AI机器翻译,仅供参考!

    相关内容

    期刊名:Febs letters

    缩写:FEBS LETT

    ISSN:0014-5793

    e-ISSN:1873-3468

    IF/分区:3.0/Q2

    文章目录 更多期刊信息

    全文链接
    引文链接
    复制
    已复制!
    推荐内容
    Requirements of basic amino acid residues within the lectin-like domain of LOX-1 for the binding of oxidized low-density lipoprotein