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Neuron. 1998 Aug;21(2):305-15. doi: 10.1016/s0896-6273(00)80540-1 Q115.02025

BDNF regulates reelin expression and Cajal-Retzius cell development in the cerebral cortex

脑源性神经营养因子调节雷尔蛋白的表达和Cajal-Retzius细胞的发育 翻译改进

T Ringstedt  1, S Linnarsson, J Wagner, U Lendahl, Z Kokaia, E Arenas, P Ernfors, C F Ibáñez

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  • 1 Department of Neuroscience, Karolinska Institute, Stockholm, Sweden. thomas.ringstedt@mbb.ki.se
  • DOI: 10.1016/s0896-6273(00)80540-1 PMID: 9728912

    摘要 Ai翻译

    Cajal-Retzius (CR) cells of the cerebral cortex express receptors for the neurotrophin brain-derived neurotrophic factor (BDNF) and downregulate expression of the extracellular matrix protein Reelin during early postnatal development, coincident with the onset of cortical BDNF expression. During this period, mice lacking BDNF have elevated levels of Reelin in CR cells. Acute BDNF stimulation of cortical neuron cultures and overexpression of BDNF in the dev... ...点击完成人机验证后继续浏览
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    期刊名:Neuron

    缩写:NEURON

    ISSN:0896-6273

    e-ISSN:1097-4199

    IF/分区:15.0/Q1

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    BDNF regulates reelin expression and Cajal-Retzius cell development in the cerebral cortex