Alterations in immunized antigens of Anisakis pegreffii by ampicillin-induced gut microbiome changes in mice [0.03%]
氨苄西林诱发的小鼠肠道菌群变化对Anisakis pegreffii抗原免疫性的改变
Myungjun Kim,Jun Ho Choi,Myung-Hee Yi et al.
Myungjun Kim et al.
The gut microbiome plays an essential role in host immune responses, including allergic reactions. However, commensal gut microbiota is extremely sensitive to antibiotics and excessive usage can cause microbial dysbiosis. Herein, we investi...
Proteome identification of common immunological proteins of two nematode parasites [0.03%]
两种线虫寄生虫常见免疫蛋白的蛋白质组鉴定
Shin Ae Kang,Hak Sun Yu
Shin Ae Kang
Although helminth parasites have different life cycles, their hosts share similar immune responses involving Th2 cell-type. Here, we extracted proteins from the larvae of Anisakis simplex complex and Trichinella spiralis to identify common ...
Identification of the protease inhibitory domain of Trichinella spiralis novel cystatin (TsCstN) [0.03%]
螺旋状盘管线虫新型半胱氨酸蛋白酶抑制剂(TsCstN)抑酶肽段的鉴定
Thassanee Yuthithum,Orawan Phuphisut,Onrapak Reamtong et al.
Thassanee Yuthithum et al.
The Trichinella spiralis novel cystatin (TsCstN) inhibits cathepsin L (CatL) activity and inflammation of macrophages during lipopolysaccharide (LPS) induction. To identify the protease inhibitory region, this study applied an in silico mod...
Eunsol Lee,Seon-Ok Back,Young-Ju Lee et al.
Eunsol Lee et al.
We developed a new concentration kit, called the ParaEgg (PE), for easy detection trematode eggs from fecal samples in endemic areas of clonorchiasis and metagonimiasis in Korea. To create a standard of detection efficiency, 120 fecal sampl...
Sylvatrie-Danne Dinzouna-Boutamba,Zin Moon,Sanghyun Lee et al.
Sylvatrie-Danne Dinzouna-Boutamba et al.
Plasmodium vivax variant interspersed repeats (vir) refer to the key protein used for escaping the host immune system. Knowledge in the genetic variation of vir genes can be used for the development of vaccines or diagnostic methods. Theref...
Genetic structure of apical membrane antigen-1 in Plasmodium falciparum isolates from Pakistan [0.03%]
巴基斯坦疟原虫顶端膜抗原-1的遗传结构
Komal Zaib,Asifullah Khan,Muhammad Umair Khan et al.
Komal Zaib et al.
Plasmodium falciparum apical membrane antigen-1 (PfAMA-1) is a major candidate for the blood-stage malaria vaccine. Genetic polymorphisms of global pfama-1suggest that the genetic diversity of the gene can disturb effective vaccine developm...
Molecular survey of Toxoplasma gondii B1 gene in pigs from various localities in Korea [0.03%]
韩国各地猪源弓形虫B1基因分子调查
Dongmi Kwak,Min-Goo Seo
Dongmi Kwak
Toxoplasma gondii, a common protozoan parasite, poses significant public health risks due to its potential to cause toxoplasmosis in humans and can be contracted from pigs, which are considered its critical intermediate host. The aim of thi...
Dynamin 2-mediated endocytosis of BLT1 is required for IL-8 production in HMC-1 cells induced by Trichomonas vaginalis-derived secretory products [0.03%]
阴道毛滴虫分泌产物诱导HMC-1细胞产生IL-8与BLT1的内吞作用相关
Young Ah Lee,Myeong Heon Shin
Young Ah Lee
We previously reported that leukotriene B4 (LTB4) contained in Trichomonas vaginalis-derived secretory products (TvSP) play an essential role in interleukin-8 (IL-8) production in human mast cell line (HMC-1 cells) via LTB4 receptor (BLT)-m...
CysLT receptor-mediated NOX2 activation is required for IL-8 production in HMC-1 cells induced by Trichomonas vaginalis-derived secretory products [0.03%]
阴道毛滴虫分泌产物诱导HMC-1细胞产生IL-8依赖于半胱氨酸白三烯受体介导的NOX2活化作用
Young Ah Lee,Myeong Heon Shin
Young Ah Lee
Trichomoniasis is caused by a sexually transmitted flagellate protozoan parasite Trichomonas vaginalis. T. vaginalis-derived secretory products (TvSP) contain lipid mediators such as leukotriene B4 (LTB4) and various cysteinyl leukotrienes ...
Yukifumi Nawa,Mio Tanaka,Masahide Yoshikawa
Yukifumi Nawa
Sparganosis is one of the common zoonotic diseases caused by infection with the larval plerocercoids (spargana) of the cestode genus Spirometra. While this parasite distributes globally in canine and feline hosts, human infection is predomi...