Yamin Lai,Jiachun Pan,Kaixin Peng et al.
Yamin Lai et al.
Drug-target Mendelian randomisation applied to metabolic dysfunction-associated steatotic liver disease: opportunities and challenges [0.03%]
药物靶点孟德尔随机化在代谢功能异常相关肝脂肪变性疾病中的应用:机遇与挑战
Shan Luo,Ming-Hua Zheng,Vincent Wai-Sun Wong et al.
Shan Luo et al.
Metabolic dysfunction-associated steatotic liver disease (MASLD) has emerged as the most prevalent cause of chronic liver disease worldwide affecting over one-third of the adult population. Despite the recent evolution of new nomenclature a...
Early clinical predictors of infected pancreatic necrosis: a multicentre cohort study [0.03%]
感染性坏死性胰腺炎的早期临床预测因素:一项多中心队列研究
Kai Song,Wenhua He,Zuoyan Wu et al.
Kai Song et al.
Background: Infected pancreatic necrosis (IPN) exacerbates complications in patients with acute pancreatitis (AP), increasing mortality rates if not treated promptly. We aimed to evaluate the predictive value of clinical ...
Essential roles of the unfolded protein response in intestinal physiology [0.03%]
未折叠蛋白反应在肠生理学中的重要作用
Claudio Hetz,Juan Francisco Silva-Agüero,Lisa M Ellerby
Claudio Hetz
The intestinal epithelium serves as an essential interface between the host and microbiota, regulating innate and adaptive immunity, absorption of nutrients and systemic metabolism, and mediating bidirectional communication with the nervous...
Faecal microbiota transplantation for eradicating Helicobacter pylori infection: clinical practice and theoretical postulation [0.03%]
粪菌移植可否成为根除幽门螺杆菌感染的新方法?临床实践和理论推测
Zhi-Ning Ye,Guy D Eslick,Shao-Gang Huang et al.
Zhi-Ning Ye et al.
The sustained increase in antibiotic resistance leads to a declining trend in the eradication rate of Helicobacter pylori (H. pylori) infection with antibiotic-based eradication regimens. Administration of a single probiotic shows limited e...
Metabolic dysfunction-associated fatty liver disease increases risk of chronic kidney disease: a systematic review and meta-analysis [0.03%]
代谢功能紊乱相关脂肪肝病增加慢性肾病风险:系统评价和.meta.分析
Jianghua Zhou,Dan-Qin Sun,Giovanni Targher et al.
Jianghua Zhou et al.
Background and aim: Metabolic dysfunction-associated fatty liver disease (MAFLD) is an alternative description and classification of non-alcoholic fatty liver disease (NAFLD) that may have better utility than NAFLD in cli...
Taking science to cholera in Bangladesh: the personal odyssey of Dr William B Greenough III and his colleagues [0.03%]
威廉·B·格林诺夫三世医生及其同事在孟加拉国的霍乱面前坚持科学之路:一段个人经历
William B Greenough Iii,Niloufar Shababi,Sanaz Nourmohammadi Abadchi
William B Greenough Iii
Cholera is one of the most rapidly fatal infectious diseases known. Historically, two major problems have been faced by those who care for patients with cholera: first, how to treat individual patients to prevent rapid death, and second, ho...
Gut microbiota and immune alteration in cancer development: implication for immunotherapy [0.03%]
肠道菌群与免疫系统在癌症发生发展中的作用及对免疫治疗的启示
Harry Cheuk Hay Lau,Xiang Zhang,Jun Yu
Harry Cheuk Hay Lau
Human gastrointestinal tract harbours trillions of microbes to form the gut microbiota. Through interacting with host cells, gut microbes play critical roles in host physiology and function. On the other hand, an altered or dysbiotic microb...
Bo-Göran Ericzon,Guoyue Lv,John W Harmon
Bo-Göran Ericzon
Emad M El-Omar
Emad M El-Omar