Spleen stiffness measurement as a non-invasive assessment in patients with portal hypertension [0.03%]
肝硬化门静脉高压患者脾硬度测定的无创性评估价值研究
Xiaoming Xu,Jiacheng Liu,Yixuan Zhu et al.
Xiaoming Xu et al.
For patients with advanced chronic liver disease who are in a compensated state, the development of portal hypertension (PHT) can lead to a heightened risk of hepatic decompensation and mortality. This underscores the importance of timely a...
Prebiotic selection influencing inflammatory bowel disease treatment outcomes: a review of the preclinical and clinical evidence [0.03%]
影响炎症性肠病治疗效果的益生元选择：对临床前和临床证据的回顾
Amin Ariaee,Sabrina Koentgen,Hannah R Wardill et al.
Amin Ariaee et al.
Inflammatory bowel disease (IBD) is characterised by chronic inflammation in the gastrointestinal tract, with unclear aetiology but with known factors contributing to the disease, including genetics, immune responses, environmental factors ...
PFDN6 contributes to colorectal cancer progression via transcriptional regulation [0.03%]
PFDN6通过转录调控促进结直肠癌进展
Fenghua Xu,LingYang Kong,Xiao Sun et al.
Fenghua Xu et al.
Objective: Colorectal cancer (CRC) is a common cancer worldwide. Although there are several treatments for cancer, the therapeutic effect on CRC remains unsatisfactory, and it is imperative to identify new therapeutic tar...
Mendelian randomisation analysis for intestinal disease: achievement and future [0.03%]
孟德尔随机化在肠病学研究中的应用：成果与展望
Xixian Ruan,Tianyi Che,Xuejie Chen et al.
Xixian Ruan et al.
Intestinal disease is a group of complex digestive system diseases imposing a significant burden globally. Identifying the risk factors and potential complications of intestinal disease is important for its prevention and treatment. However...
Endoscopic resection of large non-pedunculated colorectal polyps: current standards of treatment [0.03%]
扁平状巨大结肠息肉内镜下切除的治疗标准
Mahsa Taghiakbari,Dong Hyun Danny Kim,Roupen Djinbachian et al.
Mahsa Taghiakbari et al.
Colorectal cancer is a significant public health concern, and large non-pedunculated colorectal polyps pose a substantial risk for malignancy and incomplete resection, which may lead to interval cancer. The choice of resection technique is ...
Massimiliano Cocca,Barbara Testoni
Massimiliano Cocca
Chronic hepatitis B is the leading cause of hepatocellular carcinoma and a significant global health issue, affecting over 296 million people worldwide, with 15 million people coinfected with hepatitis delta virus (HDV) suffering accelerate...
Causal role of the gut microbiome in certain human diseases: a narrative review [0.03%]
肠道微生物组在某些人类疾病中的作用：叙述性综述
Connor Prosty,Khaled Katergi,Jesse Papenburg et al.
Connor Prosty et al.
Composed of an elaborate ecosystem of bacteria, fungi, viruses and protozoa residing in the human digestive tract, the gut microbiome influences metabolism, immune modulation, bile acid homeostasis and host defence. Through observational an...
Artificial intelligence-enabled advanced endoscopic imaging to assess deep healing in inflammatory bowel disease [0.03%]
人工智能内镜成像技术评估炎症性肠病深层愈合的效果研究
Yasuharu Maeda,Ilaria Ditonno,Miguel Puga-Tejada et al.
Yasuharu Maeda et al.
Endoscopic remission is the primary long-term therapeutic goal in inflammatory bowel disease (IBD). The assessment of this therapeutic target typically relies on white light endoscopy (WLE) combined with histological sampling. Nonetheless, ...
Pancreatic incidentaloma: incidental findings from history towards the era of liquid biopsy [0.03%]
胰腺意外瘤：从历史到液体活检时代的偶然发现
J-Matthias Löhr,Miroslav Vujasinovic,Nikolaos Kartalis et al.
J-Matthias Löhr et al.
This report provides an overview of the most common diagnostic methods that bring to light incidental findings of pancreatic cancer. It reviews the impact of medical imaging and genetic assessment on the definitions of incidental findings a...
Evidence-based incorporation of key parameters into MELD score for acute-on-chronic liver failure [0.03%]
基于证据的急性-on-慢性肝功能衰竭关键参数纳入MELD评分
Xia Yu,Ruoqi Zhou,Wenting Tan et al.
Xia Yu et al.
Background: The model for end-stage liver disease (MELD) score is widely used for the prognostication in end-stage liver disease but has limited performance in acute-on-chronic liver failure (ACLF). In this study, we iden...