Mohammed Eslam,Jacob George
Mohammed Eslam
To provide clarity for research studies and clinical care, a set of positive criteria for adults and children with metabolic (dysfunction) associated fatty liver disease (MAFLD) was recently published and has subsequently been widely endors...
Advances in the diagnosis and management of hepatorenal syndrome: insights into HRS-AKI and liver transplantation [0.03%]
肝肾综合征的诊断和治疗进展：HRS-AKI与肝脏移植的新见解
Jorge Arnold,Eduardo Avila,Francisco Idalsoaga et al.
Jorge Arnold et al.
In hepatorenal syndrome-acute kidney injury (HRS-AKI), accurate and early diagnosis is crucial. HRS is a severe condition seen in advanced cirrhosis, requiring prompt recognition and proper management to enhance patient outcomes. Diagnosis ...
Lanlan Chen,Guoyue Lv
Lanlan Chen
Recent studies have decoded the human Y chromosome sequencing with predominant precision and coverage, offering promising prospects in human genetics and clinical translation. Such an achievement is facilitated by third-generation sequencin...
Aetiology, diagnosis and management for ischaemic cholecystitis: current perspectives [0.03%]
缺血性胆囊炎的病因、诊断和治疗：当前观点
Juan Gerardo Favela,Madison B Argo,Sergio Huerta
Juan Gerardo Favela
In the absence of gallstones or any other form of mechanical obstruction, hypoperfusion to the gallbladder can lead to inflammation, ischaemia and perforation. This constellation of findings has historically been simply referred to as 'acal...
New therapeutic target for alcohol-associated hepatitis (AH): AH-associated IL-8+ neutrophils [0.03%]
酒精性肝炎（AH）相关IL-8+中性粒细胞可作为新的治疗靶点
Yukun Guan,Dechun Feng,Luca Maccioni et al.
Yukun Guan et al.
Cell-to-cell and organ-to-organ crosstalk in the pathogenesis of alcohol-associated liver disease [0.03%]
酒精相关性肝病发病机制中的细胞间及器官间相互作用
Hui Gao,Yanchao Jiang,Ge Zeng et al.
Hui Gao et al.
Alcohol-associated liver disease (ALD) is a growing global health concern and its prevalence and severity are increasing steadily. While bacterial endotoxin translocation into the portal circulation is a well-established key factor, recent ...
Xiubin Liang,Xia Hou,Y Eugene Chen et al.
Xiubin Liang et al.
Background: Cystic fibrosis (CF) is an autosomal recessive genetic disorder caused by loss-of-function mutations in the CF transmembrane conductance regulator gene. CF-related pancreatic lesions are known to cause exocrin...
Goblet cells: guardians of gut immunity and their role in gastrointestinal diseases [0.03%]
杯状细胞：肠道免疫的守护者及其在胃肠疾病中的作用
Fernanda Raya Tonetti,Alvaro Eguileor,Cristina Llorente
Fernanda Raya Tonetti
Goblet cells (GCs) are specialised guardians lining the intestine. They play a critical role in gut defence and immune regulation. GCs continuously secrete mucus creating a physical barrier to protect from pathogens while harbouring symbiot...
Lysosomal physiology and pancreatic lysosomal stress in diabetes mellitus [0.03%]
溶酶体生理和胰腺溶酶体应激在糖尿病中的作用
Meihua Hao,Sara C Sebag,Qingwen Qian et al.
Meihua Hao et al.
Endocrine and exocrine functions of the pancreas control nutritional absorption, utilisation and systemic metabolic homeostasis. Under basal conditions, the lysosome is pivotal in regulating intracellular organelles and metabolite turnover....
Characterisation of HBV and co-infection with HDV and HIV through spatial transcriptomics [0.03%]
通过空间转录组学表征HBV和HDV及HIV的合并感染
Amy Cross,James M Harris,Edward Arbe-Barnes et al.
Amy Cross et al.
Background and aims: The intrahepatic processes associated with chronic hepatitis B (CHB), especially in the context of hepatitis delta virus (HDV) and HIV co-infection, require a better understanding. Spatial transcripto...