A real-world data challenge: guidance for aligning data privacy compliance and fit-for-purpose usability [0.03%]
来自现实世界的挑战：指导数据隐私合规性和符合目的的可用性一致性的方法
Dena H Jaffe,Bradley A Malin,Rachele M Hendricks-Sturrup
Dena H Jaffe
The growing use of real-world data (RWD), particularly from electronic health records (EHRs), has heightened the need for careful attention to data privacy, utility, and transparency. We examine the complex processes involved in curating pr...
The unintended consequences of the inflation reduction act on biosimilar market incentives and Medicare savings [0.03%]
关于通胀减少法案对生物类似药市场激励及医疗保险节省的意外影响
Molly T Beinfeld,Priyanka Ghule,Fariel LaMountain et al.
Molly T Beinfeld et al.
Introduction: The Inflation Reduction Act (IRA) authorizes Medicare price negotiation but includes a "special rule" deferring negotiation for biologics with "imminent" biosimilar competition. This study examined the poten...
Specialists are central to patient chronic condition care: Medicare ACOs must adapt to this reality [0.03%]
专科医生是医疗保险病人慢性病治疗的核心：医疗协会必须适应这一现实
Kenton J Johnston,Alexander O Everhart,Peter F Lyu et al.
Kenton J Johnston et al.
The accountable care organization (ACO) model centers around primary care providers (PCPs) and undervalues the central role that specialists play for many beneficiaries with chronic conditions. This assumption informs beneficiary attributio...
Kirsten Axelsen,Delphine Courmier,Ge Bai et al.
Kirsten Axelsen et al.
We reflect on how Medicare Part D formulary design could facilitate access to biosimilars, create cost-savings, and motivate investment in biosimilar development. We evaluated adalimumab, a self-administered biologic for inflammatory condit...
Prescription drug monitoring programs and perioperative opioid prescribing and adverse events [0.03%]
处方药监控项目与围手术期阿片类药物开具及不良事件的关系研究
Joanne Constantin,Jennifer Waljee,Thuy Nguyen et al.
Joanne Constantin et al.
Introduction: Most states mandate clinicians to review prescription drug monitoring program (PDMP) databases before prescribing opioids, but the association with perioperative outcomes is unknown. ...
David B Muhlestein
David B Muhlestein
Michael Anne Kyle,Kimberly Y Feng,Carrie G Wade et al.
Michael Anne Kyle et al.
Introduction: High administrative costs are a notable feature and frustration of the American health care system. Administrative complexity drives excess health care spending and clinician burnout. There is growing intere...
Andrea Odinakachukwu Orji
Andrea Odinakachukwu Orji
The long-term services and supports (LTSS) system is intended to grant Americans, requiring care that extends beyond what can be provided in a hospital and/or primary care settings alone, access to the appropriate caretakers and facilities....
S Sean Tu,Arti Rai,Aaron S Kesselheim
S Sean Tu
Recent policy shifts at the U.S. Patent and Trademark Office (USPTO) have sharply limited the use of two administrative pathways for patent reviews, inter partes review (IPR) and post-grant review (PGR). Congress created these administrativ...
Ari Ne&#x;eman,Alex Brooks,Kellie Hans-Green et al.
Ari Ne&#x;eman et al.
Introduction: Foster care admissions are highly traumatic for children and their families, often causing serious adverse outcomes. We seek to assess the viability of machine learning methods to identify children at risk o...