Postnatal Neuronal Nogo-A Knockdown Decreased the Message of Glutamatergic Synaptic Proteins [0.03%]
产后Nogo-A敲低减少谷氨酸能突触蛋白 mRNA 的表达
Alicia M Case,Jonathan D Lautz,Son T Ton et al.
Alicia M Case et al.
It is well known that oligodendrocyte-associated Nogo-A protein is an important regulator of axonal outgrowth and an important inhibitor of functional recovery and anatomical plasticity after central nervous system (CNS) injury. Abundant st...
The Role of the Orbitofrontal Cortex in the Regulation of Fear Coping Strategies [0.03%]
眶额皮质在恐惧应对策略调节中的作用
Hsun-Yi Kuan,Chun-Hui Chang
Hsun-Yi Kuan
Under threats, individuals exhibit freezing behavior and prepare for active coping. The ability to flexibly shift between freezing and active coping increases survival chances in animals and decreases susceptibility to mental disorders amon...
Exogenous Janus Kinase 617 Codon Influences Small Noncoding RNAs and Gene Expression in Ba/F3 Cells [0.03%]
外源性Janus激酶第617密码子影响Ba/F3细胞中小非编码RNA和基因表达
Yi-Yang Chen,Ying-Hsuan Wang,Chih-Cheng Chen et al.
Yi-Yang Chen et al.
Myeloproliferative neoplasms (MPNs) are blood cancers caused by mutations that originate from hematopoietic stem cells. More than 50%-90% of MPN patients had a dominant negative valine (V) to phenylalanine (F) mutation at the Janus kinase 6...
Elevations of N-Terminal Mid-Fragment of Osteocalcin and Cystatin C Levels are Associated with Disorders of Glycolipid Metabolism and Abnormal Bone Metabolism in Patients with Type 2 Diabetes Mellitus Complicated with Osteoporosis [0.03%]
骨代谢异常的2型糖尿病合并骨质疏松患者Ⅰ型胶原C端肽、骨钙素N端中分子量片段和胱抑素C水平的变化及其临床意义
Xiaofang Guo,Yun Shen,Teng Du et al.
Xiaofang Guo et al.
Type 2 diabetes mellitus (T2DM) patients always develop osteoporosis (OP). We examined correlations of N-terminal mid-fragment of osteocalcin (N-MID) and cystatin C (Cys C) levels with glycolipid metabolism, bone metabolism markers, and bon...
Pu-Yeh Wu,Cheng-Chang Lien
Pu-Yeh Wu
Interstitial pH fluctuations occur normally in the brain and significantly modulate neuronal functions. Acid-sensing ion channels (ASICs), which serve as neuronal acid chemosensors, play important roles in synaptic plasticity, learning, and...
The Impact of Different Muscle Relaxation Techniques on the Upper Trapezius and Its Relationship with the Middle Trapezius [0.03%]
不同肌筋膜放松技术对上斜方肌的影响及其与中斜方肌的关联性研究
Gao Li,Dan Liu,Di Yang et al.
Gao Li et al.
The relaxation of trapezius muscles is widely believed to alleviate fatigue or injury of the trapezius muscles and reduce the risk of shoulder and neck pain. This study aims to examine the effects of different muscle relaxation techniques o...
Randomized Controlled Trial
Journal of physiological investigation. 2024 Jul 1;67(4):225-232. DOI:10.4103/ejpi.EJPI-D-24-00041 2024
Allicin Mitigates Diabetic Retinopathy in Rats by Activating Phosphatase and Tensin Homolog-induced Kinase 1/Parkin-mitophagy and Inhibiting Oxidative Stress-mediated NOD-like Receptor Family Pyrin Domain Containing 3 Inflammasome [0.03%]
大蒜素通过激活PTEN诱导的激酶1/Parkin线粒体自噬和抑制NLRP3炎性小体相关氧化应激减轻糖尿病大鼠视网膜病变
Yuanyuan Xu,Jia Yu
Yuanyuan Xu
Diabetic retinopathy (DR) is one of the significant disabling outcomes of diabetes mellitus characterized by retinal microvascular damage, inflammation, and neuronal dysfunction. Allicin (Alc), a natural compound found in garlic, has garner...
Purine-rich Element-binding Protein B Mediates Ferroptosis in Lipopolysaccharide-induced Raw264.7 Macrophage Inflammation [0.03%]
富嘌呤元件结合蛋白B介导脂多糖诱导的RAW264.7巨噬细胞炎症中的铁死亡
Zhaosi Wang,Wei Zhang,Xiangrui Zhu et al.
Zhaosi Wang et al.
Lipopolysaccharide (LPS) plays an important role in Raw264.7 macrophage ferroptosis and inflammation. Purine-rich element-binding protein B (Purb) influences cellular processes by regulating gene expression as a transcription factor. Howeve...
Functional Role of DDR1 in Oligodendrocyte Signaling Mechanism in Association with Myelination and Remyelination Process in the Central Nerve System [0.03%]
DDR1在中枢神经系统髓鞘和再髓鞘过程中的功能作用及在少突胶质细胞信号机制中的作用
Mariadoss Arokia Vijaya Anand,Kumar Shivamadhaiah Manjula,Chau-Zen Wang
Mariadoss Arokia Vijaya Anand
Multiple sclerosis (MS) is a complicated, inflammatory disease that causes demyelination of the central nervous system (CNS), resulting in a variety of neurological abnormalities. Over the past several decades, different animal models have ...
The Impact of Highly Selective Thoracic Sympathectomy on the Progression of Monocrotaline-induced Pulmonary Arterial Hypertension in Rats [0.03%]
胸交感神经离断术对肺动脉高压大鼠疾病进展影响的实验研究
Wuqianhui Liu,Chen Men,Zibo Liu et al.
Wuqianhui Liu et al.
Pulmonary arterial hypertension (PAH) is characterized by persistently elevated pulmonary artery pressure and vascular resistance. Sympathetic overactivity in hypertension participates in pulmonary vascular remodeling and heart failure. The...