CircRNA-0013747 Promotes Mesangial Cell Proliferation in Immunoglobulin A Nephropathy through Modulation of the Warburg Effect [0.03%]
Circular RNA-0013747通过调节瓦尔堡效应促进免疫球蛋白A肾病的系膜细胞增殖
Huimei Zou,Wenli Deng,Lifen Xu et al.
Huimei Zou et al.
Immunoglobulin A nephropathy (IgAN) is characterized by aberrant mesangial cell (MC) proliferation, which is a critical determinant of glomerular sclerosis and renal dysfunction. Previous studies have highlighted the role of pyruvate kinase...
Posttraining Dry Cupping Treatment Elevates Heart Rate Variability in Taekwondo Athletes [0.03%]
训练后的干杯治疗可提高跆拳道运动员的心率变异性
Chi-Cheng Lu,Bao-Lien Hung,Ai-Chi Zheng et al.
Chi-Cheng Lu et al.
Elite taekwondo (TKD) athletes require physical strength and mastery of complex techniques to excel in a highly competitive environment. This study aimed to investigate the effects of dry cupping posttraining on heart rate variability (HRV)...
Tannic Acid Modulates Voltage-gated K+ Channels to Promote Neuritogenesis in Neuronal N2A Cells [0.03%]
棓酸通过调控电压门控钾通道促进神经元N2A细胞的轴突生长的作用及机制研究
Tien-Yao Tsai,Chin-Min Chuang,King-Chuen Wu et al.
Tien-Yao Tsai et al.
In a previous report, we showed that voltage-gated K+ (Kv) Kv1 and Kv2 channels are involved in cAMP-induced neuritogenesis of mouse neuronal N2A cells. In this report, we examined the effects of tannic acid (TA) on Kv channels and neuritog...
Neng-Jing-Huo Essential Oil Blend Inhibits Lipopolysaccharide-Induced Intracellular Reactive Oxygen Species Accumulation, Inflammation, and Apoptosis in Renal Tubular Epithelial Cells [0.03%]
宁景活复方精油通过抑制脂多糖诱导的肾小管上皮细胞内活性氧积累、炎症及凋亡发挥肾脏保护作用
Chin-Ya Su,Kai-Fu Chang,Chih-Yen Hsiao et al.
Chin-Ya Su et al.
Acute kidney injury (AKI) is a common serious complication of sepsis that is characterized by the rapid deterioration of kidney function. Neng-Jing-Huo (NJH) is an essential oil blend, including Gaultheria procumbens, Zingiber officinale, B...
Indoleamine 2,3-Dioxygenase 1/Aryl Hydrocarbon Receptor Feedback Loop Mediates Anti-inflammation in lipopolysaccharide-stimulated Astrocytes to Dampen Inflammatory Neurotoxicity [0.03%]
吲哚胺2，3-双氧酶1/芳香烃受体反馈环通过减轻炎症神经毒性介导脂多糖刺激的星形胶质细胞的抗炎作用
Yu-Ling Gan,Yi-Hsuan Lee
Yu-Ling Gan
Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that regulates cell immune responses in a cell type-specific and ligand-dependent manner. In the central nervous system, astrocytic AhR plays important roles in regu...
Apelin-13 Ameliorates Sepsis-induced Brain Injury by Activating Phosphatase and Tensin Homolog-induced Putative Kinase 1/Parkin-mediated Mitophagy and Modulating Nucleotide-binding Oligomerization Domain-like Receptor Pyrin Domain-Containing 3-driven Pyroptosis in Rats [0.03%]
阿皮林通过激活PTEN诱导的kinase 1/Parkin介导的线粒体自噬并调节NLRP3驱动的焦亡改善大鼠脓毒症引起的脑损伤
Fan Jiang,Junxia Dong,Yi Han
Fan Jiang
Sepsis is a life-threatening condition that often results in severe brain injury, primarily due to excessive inflammation and mitochondrial dysfunction. This study aims to investigate the neuroprotective effects of Apelin-13, a bioactive pe...
Age- and Urothelium-related Changes in Hydrogen Sulfide-induced Responses in Mouse Bladder [0.03%]
与年龄和尿路上皮相关的氢硫化物诱导的小鼠膀胱反应的变化
Fatma Aydinoglu,Tugba Toyran,Nuran Ogulener
Fatma Aydinoglu
The alterations in bladder function are associated with aging. Hydrogen sulfide (H2S) is a gaseous neurotransmitter that is synthesized in the urinary bladder and is suggested to regulate bladder smooth muscle tone. The effects of age and u...
Effect of Advillin Knockout on Diabetic Neuropathy Induced by Multiple Low Doses of Streptozotocin [0.03%]
Advillin基因敲除对多次小剂量链脲佐菌素诱导的糖尿病周围神经病变的影响
Yu-Chia Chuang,Bo-Yang Jiang,Chih-Cheng Chen
Yu-Chia Chuang
Advillin is an actin-binding protein involved in regulating the organization of actin filaments and the dynamics of axonal growth cones. In mice, advillin is exclusively expressed in somatosensory neurons, ubiquitously expressed in all neur...
Neuroprotective Role of Transchalcone in Parkinson's Disease through AMP-activated Protein Kinase-mediated Signaling Pathway [0.03%]
茋查尔酮通过AMP活化蛋白激酶介导的信号通路在帕金森病中的神经保护作用
Yao Cheng,Shaik Althaf Hussain,Turki Mayudh Alrubie et al.
Yao Cheng et al.
Parkinson's disease (PD) is a gradually worsening neurodegenerative condition marked by the deterioration of dopaminergic neurons, motor dysfunction, and mitochondrial dysfunction. Trans-chalcone, a natural flavonoid, has shown promise in v...
Exploring the Effects of Tomatidine ((3β, 5α, 22β, and 25β)-Spirosolan-3-ol) on Voltage-gated Na+ currents: Insights Into Its Ionic Mechanisms of Action on Current Magnitude, Gating, and Frequency Dependence [0.03%]
番茄胺((3β, 5α, 22β, 和 25β)- Spirosolan-3-ol)对电压门控Na+电流的影响：关于其离子作用机制的见解，包括对电流幅度、闸门和频率依赖性的影响
Tso-Lin Lin,Edmund Cheung So,Sheng-Nan Wu
Tso-Lin Lin
Tomatidine, a major tomato glycoalkaloid, is effective for the prevention of skeletal muscle wasting and enhancing mitophagy. However, its effects on transmembrane ionic currents are not well explored. In this study, we explored the interac...